HitPredict

Interactor 1: PARP1 (P09874)
Poly [ADP-ribose] polymerase 1 (PARP-1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 1) (ARTD1) (DNA ADP-ribosyltransferase PARP1) (EC 2.4.2.-) (NAD(+) ADP-ribosyltransferase 1) (ADPRT 1) (Poly[ADP-ribose] synthase 1) (Protein poly-ADP-ribosyltransferase PARP1) (EC 2.4.2.-) [Cleaved into: Poly [ADP-ribose] polymerase 1, processed C-terminus (Poly [ADP-ribose] polymerase 1, 89-kDa form); Poly [ADP-ribose] polymerase 1, processed N-terminus (NT-PARP-1) (Poly [ADP-ribose] polymerase 1, 24-kDa form) (Poly [ADP-ribose] polymerase 1, 28-kDa form)]
Gene: PARP1

Interactor 2: UBP36 (Q9P275)
Ubiquitin carboxyl-terminal hydrolase 36 (EC 2.3.2.-) (EC 3.4.19.12) (Deubiquitinating enzyme 36) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36)
Gene: USP36

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.650

Property	Details
Experiments	34079125, 36912080, 19615732
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0005829 - cytosol
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 1014 Hs			1 1123
+	Hs
		1187833 ZCCHV_HUMAN (798-1005): 5.42e-21: 101: 15.71		UBP36_HUMAN (1-1123): 0: 646: 100.00
+	Hs
		1188883 PARPT_HUMAN (710-1006): 4.56e-65: 234: 15.84		UBP42_HUMAN (1-1023): 1.74e-104: 359: 31.00
+	Hs
		1173846 PARPT_HUMAN (710-1006): 4.56e-65: 234: 15.84		UBP34_HUMAN (8-456): 3.65e-95: 337: 19.51