Interactor 1: RPAC1 (P07703)
DNA-directed RNA polymerases I and III subunit RPAC1 (RNA polymerases I and III subunit AC1) (C37) (DNA-directed RNA polymerases I and III 40 kDa polypeptide) (AC40) (C40)
Gene: RPC40

Interactor 2: RPA2 (P22138)
DNA-directed RNA polymerase I subunit RPA135 (EC 2.7.7.6) (DNA-directed RNA polymerase I 135 kDa polypeptide) (A135) (DNA-directed RNA polymerase I polypeptide 2) (RNA polymerase I subunit 2)
Gene: RPA135

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.976

The method score is based on:

Property Details
Experiments 10393904, 11805826, 11805837, 16554755, 16429126, 37968396, 22940862, 23209026, 31851481, 14759368
Identification Methods two hybrid, tandem affinity purification, anti tag coimmunoprecipitation, affinity chromatography technology, cross-linking study
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_pol_L~RNA_pol_Rpb2_6
Common GO terms GO:0003677 - DNA binding
GO:0003899 - DNA-directed RNA polymerase activity
GO:0005634 - nucleus
GO:0005736 - RNA polymerase I complex
GO:0006360 - transcription by RNA polymerase I
and 5 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 335
Sc

1 1203
+ Sc
+ Hs
+ Hs
+ Sc
+ Hs
+ Hs
+ Sc
+ Hs
+ Dm
+ Dm
+ Hs
+ Sc
+ Sp
+ Sc
+ Pf
+ Hv
+ Hv

Service provided by Combinatics, Japan

Last updated: 11Aug2025