HitPredict

Interactor 1: HYBG (P0AAM7)
Hydrogenase maturation factor HybG (Hydrogenase-2 operon protein HybG)
Gene: HYBG

Interactor 2: HYPD (P24192)
Hydrogenase maturation factor HypD (Hydrogenase isoenzymes formation protein HypD)
Gene: HYPD

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.67	1.00	0.822

Property	Details
Experiments	24561554, 16412426
Identification Methods	two hybrid, affinity chromatography technology, pull down, two hybrid array, luminescence based mammalian interactome mapping
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	HupF_HypC~HypD
Common GO terms	GO:0005506 - iron ion binding GO:0051604 - protein maturation GO:0065003 - protein-containing complex assembly
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 82 Ec			1 373
+	Ec
		465951 HYPC_ECOLI (1-75): 3.13e-27: 96.3: 55.84		HYPD_ECOLI (1-373): 0: 603: 100.00
+	Nv
		1175711 Q72AR8_NITV2 (1-73): 6.95e-24: 87.5: 28.77		Q72F89_NITV2 (3-366): 0: 537: 45.75
+	Tk
		1126839 Q5JII0_THEKO (1-76): 2.16e-24: 88.6: 36.84		Q5JII1_THEKO (5-366): 0: 521: 38.21