HitPredict

Interactor 1: HNS (P0ACF8)
DNA-binding protein H-NS (Heat-stable nucleoid-structuring protein) (Histone-like protein HLP-II) (Protein B1) (Protein H1)
Gene: HNS

Interactor 2: STPA (P0ACG1)
DNA-binding protein StpA (H-NS homolog StpA)
Gene: STPA

Species: Escherichia coli K-12

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.81 0.60 0.697

The method score is based on:

Property Details
Experiments 16606699, 24561554, 19402753, 15690043
Identification Methods affinity chromatography technology, two hybrid, tandem affinity purification, pull down, two hybrid array
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000976 - transcription cis-regulatory region binding
GO:0001217 - DNA-binding transcription repressor activity
GO:0003680 - minor groove of adenine-thymine-rich DNA binding
GO:0003681 - bent DNA binding
GO:0003723 - RNA binding
and 4 others

more...
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 137
Ec

1 134
+ Sf
+ Sf
+ Sf
+ Ec
+ Se
+ Ec

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024