Interactor 1: MDR1 (P08183)
ATP-dependent translocase ABCB1 (ATP-binding cassette sub-family B member 1) (Multidrug resistance protein 1) (EC 7.6.2.2) (P-glycoprotein 1) (Phospholipid transporter ABCB1) (EC 7.6.2.1) (CD antigen CD243)
Gene: ABCB1

Interactor 2: MDR3 (P21439)
Phosphatidylcholine translocator ABCB4 (EC 7.6.2.1) (ATP-binding cassette sub-family B member 4) (Multidrug resistance protein 3) (P-glycoprotein 3)
Gene: ABCB4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 35575683
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains ABC_membrane~ABC_membrane, ABC_membrane~ABC_tran, ABC_tran~ABC_tran
Common GO terms GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0016020 - membrane
GO:0016324 - apical plasma membrane
and 6 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 1280
Hs

1 1286
+ Hs
+ At
+ Sc
+ Mm
+ Hs
+ Hs

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Last updated: 11Aug2025