Protein: STE6
Alpha-factor-transporting ATPase (EC 7.4.2.7) (Mating factor A secretion protein STE6) (Multiple drug resistance protein homolog) (P-glycoprotein)

Gene: STE6
Organism: Saccharomyces cerevisiae S288C
Interactions: 37
UniProt ID: P12866

Gene Ontology (top 5):
GO:0000324 - fungal-type vacuole
GO:0000770 - peptide pheromone export
GO:0005524 - ATP binding
GO:0005743 - mitochondrial inner membrane
GO:0005794 - Golgi apparatus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

556555

STE6
Alpha-factor-transporting ATPase

1

10

Small-scale

0.618

High

522884

HSP71
Heat shock protein SSA1

2

1

Small-scale

0.611

High

556562

CDC48
Cell division control protein 48

3

0

Small-scale

0.606

High

556573

DOA10
ERAD-associated E3 ubiquitin-protein ligase DOA10

2

2

Small-scale

0.567

High

392119

HSP82
ATP-dependent molecular chaperone HSP82

1

2

Small-scale

0.536

High

556561

MAS5
Mitochondrial protein import protein MAS5

1

0

Small-scale

0.513

High

464500

CHS1
Chitin synthase 1

1

1

High-throughput

0.479

High

525773

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.479

High

556556

PMA2
Plasma membrane ATPase 2

1

4

High-throughput

0.479

High

556560

PHO84
Inorganic phosphate transporter PHO84

1

1

High-throughput

0.479

High

556563

CHS3
Chitin synthase 3

1

1

High-throughput

0.479

High

556564

ATC5
Phospholipid-transporting ATPase DNF1

1

2

High-throughput

0.479

High

556565

SNC2
Synaptobrevin homolog 2

1

2

High-throughput

0.479

High

556568

FKS1
1,3-beta-glucan synthase component FKS1

1

1

High-throughput

0.479

High

556570

SNF7
Vacuolar-sorting protein SNF7

1

1

High-throughput

0.479

High

556574

FKS2
1,3-beta-glucan synthase component GSC2

1

1

High-throughput

0.479

High

556579

DIP5
Dicarboxylic amino acid permease

1

2

High-throughput

0.479

High

556583

ATC4
Phospholipid-transporting ATPase DNF2

1

2

High-throughput

0.479

High

556575

LEM3
Phospholipid-transporting ATPase accessory subunit LEM3

1

0

High-throughput

0.458

High

556582

HBT1
Protein HBT1

1

0

High-throughput

0.458

High

543630

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

381829

H4
Histone H4

1

1

High-throughput

0.437

High

556567

ARPC1
Actin-related protein 2/3 complex subunit 1

1

1

High-throughput

0.437

High

556576

GNP1
High-affinity glutamine permease

1

3

High-throughput

0.437

High

556584

DFM1
DER1-like family member protein 1

1

2

Small-scale

0.437

High

556569

SEC72
Translocation protein SEC72

1

0

High-throughput

0.282

High

556578

YGI1
Uncharacterized protein YGL081W

1

0

High-throughput

0.282

High

556580

VPS9
Vacuolar protein sorting-associated protein 9

1

0

High-throughput

0.282

High

556571

LSM4
LSM complex subunit LSM4

1

0

High-throughput

0.265

Low

556572

LSM5
LSM complex subunit LSM5

1

0

High-throughput

0.265

Low

556557

UBR1
E3 ubiquitin-protein ligase UBR1

1

0

Small-scale

0.249

Low

556558

SAN1
Protein SAN1

1

0

Small-scale

0.249

Low

556559

PSA2
Proteasome subunit alpha type-2

1

0

High-throughput

0.249

Low

556566

NPL4
Nuclear protein localization protein 4

1

0

Small-scale

0.249

Low

556577

UFD1
Ubiquitin fusion degradation protein 1

1

0

Small-scale

0.249

Low

556581

DID2
Vacuolar protein-sorting-associated protein 46

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025