Interactor 1: MDR1 (P08183)
ATP-dependent translocase ABCB1 (ATP-binding cassette sub-family B member 1) (Multidrug resistance protein 1) (EC 7.6.2.2) (P-glycoprotein 1) (Phospholipid transporter ABCB1) (EC 7.6.2.1) (CD antigen CD243)
Gene: ABCB1
Interactor 2: ABCB5 (Q2M3G0)
ATP-binding cassette sub-family B member 5 (ABCB5 P-gp) (P-glycoprotein ABCB5) (EC 7.6.2.2)
Gene: ABCB5
Species: Homo sapiens
Source: biogrid
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 35575683 |
| Identification Methods | cross-linking study |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | ABC_membrane~ABC_membrane, ABC_membrane~ABC_tran, ABC_tran~ABC_tran |
| Common GO terms | GO:0005524 - ATP binding GO:0005886 - plasma membrane GO:0008559 - ABC-type xenobiotic transporter activity GO:0015562 - efflux transmembrane transporter activity GO:0016324 - apical plasma membrane and 3 others more... |
| Homologous interactions | 6 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Hs |   |
|
|||||||||||
| + | At | |
|
|||||||||||
| + | Sc | |
|
|||||||||||
| + | Mm | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 11Aug2025
