HitPredict

Interactor 1: H2AZ (P0C0S5)
Histone H2A.Z (H2A/z)
Gene: H2AZ1

Interactor 2: NP1L4 (Q99733)
Nucleosome assembly protein 1-like 4 (Nucleosome assembly protein 2) (NAP-2)
Gene: NAP1L4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.776

Property	Details
Experiments	33961781, 24463511
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Histone~NAP
Common GO terms	GO:0005634 - nucleus
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 128 Hs			1 375
+	Hs
		1087091 H2A2C_HUMAN (5-127): 3.47e-55: 170: 61.29		NP1L4_HUMAN (1-375): 2.5e-142: 410: 100.00
+	Hs
		391863 H2A1B_HUMAN (5-125): 9.18e-55: 169: 61.48		NP1L4_HUMAN (1-375): 2.5e-142: 410: 100.00
+	Hs
		470518 H2A1_HUMAN (5-125): 8.23e-55: 169: 61.48		NP1L4_HUMAN (1-375): 2.5e-142: 410: 100.00
+	Mm
		470225 H2AZ_MOUSE (1-128): 9.79e-62: 186: 100.00		NP1L1_MOUSE (21-336): 1.45e-124: 366: 68.35
+	Hs
		469982 H2AZ_HUMAN (1-128): 9.79e-62: 186: 100.00		NP1L1_HUMAN (21-336): 1.38e-123: 363: 67.72
+	Hs
		876839 H2A2B_HUMAN (5-127): 9.2e-56: 171: 59.68		NP1L1_HUMAN (21-336): 1.38e-123: 363: 67.72
+	Hs
		876804 H2A2C_HUMAN (5-127): 3.47e-55: 170: 61.29		NP1L1_HUMAN (21-336): 1.38e-123: 363: 67.72
+	Hs
		391616 H2A1B_HUMAN (5-125): 9.18e-55: 169: 61.48		NP1L1_HUMAN (21-336): 1.38e-123: 363: 67.72
+	Hs
		470307 H2A1_HUMAN (5-125): 8.23e-55: 169: 61.48		NP1L1_HUMAN (21-336): 1.38e-123: 363: 67.72
+	Hs
		555373 H2AX_HUMAN (5-124): 1.08e-54: 169: 61.98		NP1L1_HUMAN (21-336): 1.38e-123: 363: 67.72
+	Ce
		1090449 H2AV_CAEEL (4-124): 1.34e-57: 176: 88.43		Q19007_CAEEL (40-363): 3.1e-91: 278: 36.70
+	Sp
		815619 H2AZ_SCHPO (18-119): 1.91e-46: 148: 78.43		YGNB_SCHPO (16-371): 2.93e-100: 303: 34.36
+	Sp
		223691 H2AZ_SCHPO (18-119): 1.91e-46: 148: 78.43		YCO6_SCHPO (33-343): 7e-94: 287: 35.78
+	Sc
		627716 H2AZ_YEAST (4-126): 3.32e-39: 129: 65.91		NAP1_YEAST (14-338): 4.8e-95: 291: 33.94
+	Hs
		469999 H2AZ_HUMAN (1-128): 9.79e-62: 186: 100.00		SET_HUMAN (92-336): 2.56e-62: 203: 20.82
+	Hs
		963845 H2AV_HUMAN (1-127): 2.06e-60: 183: 98.43		SET_HUMAN (92-336): 2.56e-62: 203: 20.82
+	Hs
		391771 H2A1B_HUMAN (5-125): 9.18e-55: 169: 61.48		TSYL5_HUMAN (112-368): 1.78e-63: 210: 15.00
+	Hs
		391896 H2A1B_HUMAN (5-125): 9.18e-55: 169: 61.48		TSYL1_HUMAN (113-336): 1.52e-63: 210: 17.86
+	Hs
		555417 H2AX_HUMAN (5-124): 1.08e-54: 169: 61.98		SET_HUMAN (92-336): 2.56e-62: 203: 20.82