Protein: SPS1
Sporulation-specific protein 1 (EC 2.7.11.1)

Gene: SPS1
Organism: Saccharomyces cerevisiae S288C
Interactions: 95
UniProt ID: P08458

Gene Ontology (top 5):
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005628 - prospore membrane
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

470109

MAS5
Mitochondrial protein import protein MAS5

2

6

High-throughput

0.754

High

470113

ARP2
Actin-related protein 2

1

9

High-throughput

0.691

High

470091

RNA1
Ran GTPase-activating protein 1

1

6

High-throughput

0.647

High

470092

YPK1
Serine/threonine-protein kinase YPK1

1

18

High-throughput

0.647

High

470093

YAK1
Dual specificity protein kinase YAK1

1

18

High-throughput

0.647

High

470133

DUN1
DNA damage response protein kinase DUN1

1

18

High-throughput

0.647

High

470144

CSK2B
Casein kinase II subunit beta

1

5

High-throughput

0.647

High

470107

SCJ1
DnaJ-related protein SCJ1

1

6

High-throughput

0.646

High

470120

MDJ1
DnaJ homolog 1, mitochondrial

1

8

High-throughput

0.646

High

470152

ACT
Actin

1

6

High-throughput

0.646

High

470110

CDC15
Cell division control protein 15

1

19

Small-scale

0.618

High

470114

HSP7F
Heat shock protein homolog SSE1

2

19

High-throughput

0.585

High

470135

CAJ1
Protein CAJ1

1

8

High-throughput

0.575

High

470095

ABP1
Actin-binding protein

1

11

High-throughput

0.536

High

470102

PP2A1
Serine/threonine-protein phosphatase PP2A-1 catalytic subunit

1

20

High-throughput

0.536

High

470103

PP2A2
Serine/threonine-protein phosphatase PP2A-2 catalytic subunit

1

20

High-throughput

0.536

High

470127

TAF5
SAGA complex/transcription factor TFIID complex subunit TAF5

1

14

High-throughput

0.536

High

470129

YHJ3
Uncharacterized protein YHR033W

1

1

High-throughput

0.536

High

470146

NMD5
Nonsense-mediated mRNA decay protein 5

1

9

High-throughput

0.536

High

470148

ARO8
Aromatic/aminoadipate aminotransferase 1

1

2

High-throughput

0.536

High

470150

PPID
Peptidyl-prolyl cis-trans isomerase CPR6

1

2

High-throughput

0.536

High

470165

AHA1
Hsp90 co-chaperone AHA1

1

3

High-throughput

0.536

High

470089

PYC1
Pyruvate carboxylase 1

1

12

High-throughput

0.515

High

470136

RV167
Reduced viability upon starvation protein 167

1

11

High-throughput

0.515

High

470155

VPS74
Vacuolar protein sorting-associated protein 74

1

0

High-throughput

0.513

High

470167

SUS1
SAGA complex subunit SUS1

1

0

High-throughput

0.513

High

416182

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

1

High-throughput

0.501

High

470116

UBC6
Ubiquitin-conjugating enzyme E2 6

1

5

High-throughput

0.501

High

470122

SDS22
Protein phosphatase 1 regulatory subunit SDS22

1

4

High-throughput

0.501

High

470134

TCPZ
T-complex protein 1 subunit zeta

1

20

High-throughput

0.501

High

470143

ARF3
ADP-ribosylation factor 3

1

8

High-throughput

0.501

High

470145

SYEC
Glutamate--tRNA ligase, cytoplasmic

1

1

High-throughput

0.501

High

470151

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

17

High-throughput

0.501

High

366891

ATPB
ATP synthase subunit beta, mitochondrial

1

7

High-throughput

0.500

High

386525

TBB
Tubulin beta chain

1

15

High-throughput

0.500

High

394122

EF1A
Elongation factor 1-alpha

1

4

High-throughput

0.500

High

452782

ATPA
ATP synthase subunit alpha, mitochondrial

1

6

High-throughput

0.500

High

470084

TBA1
Tubulin alpha-1 chain

1

12

High-throughput

0.500

High

470085

TBA3
Tubulin alpha-3 chain

1

12

High-throughput

0.500

High

470088

METK1
S-adenosylmethionine synthase 1

1

2

High-throughput

0.500

High

470096

HSP26
Heat shock protein 26

1

1

High-throughput

0.500

High

470097

VATB
V-type proton ATPase subunit B

1

8

High-throughput

0.500

High

470137

IMB4
Importin subunit beta-4

1

9

High-throughput

0.500

High

470153

PRS8
26S proteasome regulatory subunit 8 homolog

1

7

High-throughput

0.500

High

470164

HSP42
Heat shock protein 42

1

1

High-throughput

0.500

High

470166

RUVB2
RuvB-like protein 2

1

2

High-throughput

0.500

High

470118

TFC3
Transcription factor tau 138 kDa subunit

1

0

High-throughput

0.493

High

470158

SPO75
Sporulation-specific protein 75

1

0

High-throughput

0.493

High

470162

HFI1
SAGA complex subunit HFI1

1

0

High-throughput

0.493

High

470083

PRTB
Cerevisin

1

1

High-throughput

0.489

High

470100

SDHB
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial

1

1

High-throughput

0.489

High

470111

IDH1
Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial

1

1

High-throughput

0.489

High

470126

ATPG
ATP synthase subunit gamma, mitochondrial

1

2

High-throughput

0.489

High

470161

RPN8
26S proteasome regulatory subunit RPN8

1

3

High-throughput

0.489

High

470105

PSB2
Proteasome subunit beta type-2

1

4

Small-scale

0.481

High

470121

CENPA
Histone H3-like centromeric protein CSE4

1

2

Small-scale

0.481

High

470125

CDC27
Anaphase-promoting complex subunit CDC27

1

6

High-throughput

0.481

High

470099

RDS2
Regulator of drug sensitivity 2

1

0

High-throughput

0.480

High

470101

APN1
Apurinic-apyrimidinic endonuclease 1

1

0

High-throughput

0.480

High

470117

DOM34
Protein DOM34

1

0

High-throughput

0.480

High

470123

YKC3
Uncharacterized protein YKL023W

1

0

High-throughput

0.480

High

470128

PLPHP
Pyridoxal phosphate homeostasis protein

1

0

High-throughput

0.480

High

470140

DPH1
2-(3-amino-3-carboxypropyl)histidine synthase subunit 1

1

0

High-throughput

0.480

High

470147

I23O
Indoleamine 2,3-dioxygenase

1

0

High-throughput

0.480

High

470149

SGF73
SAGA complex subunit SGF73

1

0

High-throughput

0.480

High

470154

YM54
Uncharacterized protein YMR196W

1

0

High-throughput

0.480

High

470157

DIB1
Spliceosomal protein DIB1

1

0

High-throughput

0.480

High

470159

MPC54
Meiotic plaque component protein 54

1

0

High-throughput

0.480

High

470160

TMA16
Translation machinery-associated protein 16

1

0

High-throughput

0.480

High

397491

REP1
Partitioning protein REP1

1

0

High-throughput

0.479

High

408271

GAL1
Galactokinase

1

0

High-throughput

0.479

High

470112

BMH1
Protein BMH1

1

17

Small-scale

0.479

High

470119

BMH2
Protein BMH2

1

17

Small-scale

0.479

High

470132

SSP1
Sporulation-specific protein 1

1

0

Small-scale

0.458

High

470141

DSN1
Kinetochore-associated protein DSN1

1

0

Small-scale

0.458

High

357722

CYC7
Cytochrome c isoform 2

1

1

High-throughput

0.457

High

470130

HSE1
Class E vacuolar protein-sorting machinery protein HSE1

1

15

High-throughput

0.457

High

470142

PRP17
Pre-mRNA-processing factor 17

1

9

High-throughput

0.457

High

470163

RBD2
Rhomboid-type serine protease 2

1

1

High-throughput

0.457

High

368551

PMG1
Phosphoglycerate mutase 1

1

5

High-throughput

0.457

High

405003

LEU3
3-isopropylmalate dehydrogenase

1

1

High-throughput

0.457

High

470098

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial

1

3

High-throughput

0.457

High

470104

MPCP
Mitochondrial phosphate carrier protein

1

6

High-throughput

0.457

High

470108

STDH
Catabolic L-serine/threonine dehydratase [Includes: L-serine dehydratase

1

2

High-throughput

0.457

High

470086

HSP71
Heat shock protein SSA1

1

12

High-throughput

0.445

High

470087

HSP72
Heat shock protein SSA2

1

12

High-throughput

0.445

High

470090

SSB1
Ribosome-associated molecular chaperone SSB1

1

11

High-throughput

0.445

High

470131

SSZ1
Ribosome-associated complex subunit SSZ1

1

9

High-throughput

0.445

High

470138

SSB2
Ribosome-associated molecular chaperone SSB2

1

11

High-throughput

0.445

High

470156

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

9

High-throughput

0.407

High

470106

PHO84
Inorganic phosphate transporter PHO84

1

0

High-throughput

0.279

Low

470115

VATD
V-type proton ATPase subunit D

1

0

High-throughput

0.279

Low

470124

PET10
Protein PET10

1

0

High-throughput

0.279

Low

470094

BGL2
Glucan 1,3-beta-glucosidase

1

0

High-throughput

0.261

Low

470139

MPM1
Mitochondrial peculiar membrane protein 1

1

0

High-throughput

0.261

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025