HitPredict

Interactor 1: RU17 (P08621)
U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (U1-70K) (snRNP70)
Gene: SNRNP70

Interactor 2: PAN2 (Q504Q3)
PAN2-PAN3 deadenylation complex catalytic subunit PAN2 (EC 3.1.13.4) (Inactive ubiquitin carboxyl-terminal hydrolase 52) (PAB1P-dependent poly(A)-specific ribonuclease) (Poly(A)-nuclease deadenylation complex subunit 2) (PAN deadenylation complex subunit 2)
Gene: PAN2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	23398456
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PAN2_N~RRM_1
Common GO terms	GO:0005634 - nucleus
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 437 Hs			1 1202
+	Hs
		550312 PABP1_HUMAN (4-361): 7.87e-51: 183: 11.08		PAN2_HUMAN (1-1202): 0: 1135: 100.00
+	Hs
		1101982 PABP4_HUMAN (2-293): 9.81e-32: 129: 10.88		PAN2_HUMAN (1-1202): 0: 1135: 100.00
+	Sc
		403582 PABP_YEAST (2-281): 3.64e-29: 121: 12.50		PAN2_YEAST (71-1186): 3.96e-169: 532: 21.83
+	Hs
		550397 PABP1_HUMAN (4-361): 7.87e-51: 183: 11.08		UBP7_HUMAN (340-1038): 3.3e-89: 314: 12.02
+	Hs
		472951 RU17_HUMAN (1-437): 4.45e-47: 169: 100.00		UBP7_HUMAN (340-1038): 3.3e-89: 314: 12.02
+	Hs
		550525 PABP1_HUMAN (4-361): 7.87e-51: 183: 11.08		UBP22_HUMAN (462-854): 6.46e-83: 282: 12.30
+	Hs
		1356390 PPIL4_HUMAN (63-356): 5.18e-35: 137: 17.17		UBP7_HUMAN (340-1038): 3.3e-89: 314: 12.02
+	Mm
		1230590 PPIL4_MOUSE (63-343): 4.46e-31: 126: 15.90		UBP7_MOUSE (340-1038): 3.41e-89: 314: 11.89
+	Sc
		403527 PABP_YEAST (2-281): 3.64e-29: 121: 12.50		UTP7_YEAST (35-461): 1.42e-80: 277: 15.37
+	Hs
		1311686 PABP5_HUMAN (4-350): 1.78e-34: 134: 11.41		GOR_HUMAN (951-1156): 1.53e-46: 180: 21.91