Protein: PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2 (EC 3.1.13.4) (PAB1P-dependent poly(A)-specific ribonuclease) (Poly(A)-nuclease deadenylation complex subunit 2) (PAN deadenylation complex subunit 2)

Gene: PAN2
Organism: Saccharomyces cerevisiae S288C
Interactions: 68
UniProt ID: P53010

Gene Ontology (top 5):
GO:0000289 - nuclear-transcribed mRNA poly(A) tail shortening
GO:0000932 - P-body
GO:0003676 - nucleic acid binding
GO:0004535 - poly(A)-specific ribonuclease activity
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

781096

PAN3
PAN2-PAN3 deadenylation complex subunit PAN3

10

4

Small-scale

0.982

High

403582

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

3

6

Small-scale

0.853

High

545576

SSB1
Ribosome-associated molecular chaperone SSB1

2

16

High-throughput

0.552

High

776614

DEF1
RNA polymerase II degradation factor 1

1

0

High-throughput

0.518

High

509647

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

20

High-throughput

0.501

High

633490

PP11
Serine/threonine-protein phosphatase PP1-1

1

2

High-throughput

0.479

High

656545

KC11
Casein kinase I homolog 1

1

7

High-throughput

0.479

High

713009

MCM2
DNA replication licensing factor MCM2

1

3

High-throughput

0.479

High

789806

SOL2
6-phosphogluconolactonase-like protein 2

1

1

High-throughput

0.479

High

801785

KPR3
Ribose-phosphate pyrophosphokinase 3

1

1

High-throughput

0.479

High

818421

DDI1
DNA damage-inducible protein 1

1

2

High-throughput

0.479

High

894386

SOL1
6-phosphogluconolactonase-like protein 1

1

1

High-throughput

0.479

High

916397

PBP1
PAB1-binding protein 1

1

0

Small-scale

0.460

High

448112

DCTD
Deoxycytidylate deaminase

1

0

High-throughput

0.458

High

454467

PHO4
Phosphate system positive regulatory protein PHO4

1

0

High-throughput

0.458

High

531493

RT01
Small ribosomal subunit protein mS43

1

0

High-throughput

0.458

High

597749

APA1
Protein APA1 [Includes: Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase 1

1

0

High-throughput

0.458

High

654796

URE2
Transcriptional regulator URE2

1

0

High-throughput

0.458

High

668281

UBP1
Ubiquitin carboxyl-terminal hydrolase 1

1

0

High-throughput

0.458

High

752059

ECT1
Ethanolamine-phosphate cytidylyltransferase

1

0

High-throughput

0.458

High

763768

THI80
Thiamine pyrophosphokinase

1

0

High-throughput

0.458

High

804090

GIC1
GTPase-interacting component 1

1

0

High-throughput

0.458

High

816498

BUD16
Putative pyridoxal kinase BUD16

1

0

High-throughput

0.458

High

817213

FIR1
Factor interacting with REF2

1

0

High-throughput

0.458

High

823106

ATG3
Autophagy-related protein 3

1

0

High-throughput

0.458

High

844389

SERB
Phosphoserine phosphatase

1

0

High-throughput

0.458

High

916399

DOS2
Protein DOS2

1

0

High-throughput

0.458

High

916404

CSM3
Chromosome segregation in meiosis protein 3

1

0

High-throughput

0.458

High

916408

SAM4
Homocysteine S-methyltransferase 2

1

0

High-throughput

0.458

High

916409

TSR3
18S rRNA aminocarboxypropyltransferase

1

0

High-throughput

0.458

High

481691

HSP73
Heat shock protein SSA3

1

15

High-throughput

0.445

High

527190

HSP72
Heat shock protein SSA2

1

15

High-throughput

0.445

High

741983

HSP7F
Heat shock protein homolog SSE1

1

19

High-throughput

0.445

High

819270

SSB2
Ribosome-associated molecular chaperone SSB2

1

16

High-throughput

0.445

High

367074

ATPB
ATP synthase subunit beta, mitochondrial

1

7

High-throughput

0.437

High

452933

ATPA
ATP synthase subunit alpha, mitochondrial

1

7

High-throughput

0.437

High

646678

VPS15
Serine/threonine-protein kinase VPS15

1

9

High-throughput

0.437

High

700260

GAR1
H/ACA ribonucleoprotein complex subunit GAR1

1

1

High-throughput

0.437

High

792741

ETR1
Enoyl-[acyl-carrier-protein] reductase, mitochondrial

1

2

High-throughput

0.437

High

793861

SWD3
COMPASS component SWD3

1

14

High-throughput

0.437

High

830105

FKS2
1,3-beta-glucan synthase component GSC2

1

1

High-throughput

0.437

High

850547

RSC8
Chromatin structure-remodeling complex protein RSC8

1

6

High-throughput

0.437

High

867849

SSN8
RNA polymerase II holoenzyme cyclin-like subunit

1

3

High-throughput

0.437

High

916398

EF3B
Elongation factor 3B

1

3

High-throughput

0.437

High

916401

CTF4
DNA polymerase alpha-binding protein

1

10

High-throughput

0.437

High

916405

FKS3
1,3-beta-glucan synthase component FKS3

1

1

High-throughput

0.437

High

916410

CMR3
Zinc finger protein CRM3

1

4

High-throughput

0.437

High

916413

MPD1
Protein disulfide-isomerase MPD1

1

1

High-throughput

0.437

High

916412

HSP42
Heat shock protein 42

1

0

High-throughput

0.426

High

750277

PRP40
Pre-mRNA-processing protein PRP40

1

0

High-throughput

0.279

Low

314893

SEM1
26S proteasome complex subunit SEM1

1

0

High-throughput

0.269

Low

454590

TFS2
Transcription elongation factor S-II

1

0

High-throughput

0.249

Low

603592

KRE1
Protein KRE1

1

0

High-throughput

0.249

Low

605395

RTPT
Small ribosomal subunit protein mS26

1

0

High-throughput

0.249

Low

713583

RIF1
Telomere length regulator protein RIF1

1

0

High-throughput

0.249

Low

758481

SEG2
Eisosome protein SEG2

1

0

High-throughput

0.249

Low

783997

RM10
Large ribosomal subunit protein uL15m

1

0

High-throughput

0.249

Low

806686

AIM18
Altered inheritance of mitochondria protein 18, mitochondrial

1

0

High-throughput

0.249

Low

836300

BNI1
Protein BNI1

1

0

High-throughput

0.249

Low

893043

PHB2
Prohibitin-2

1

0

High-throughput

0.249

Low

909777

RL4P
Large ribosomal subunit protein uL4m

1

0

High-throughput

0.249

Low

916396

YIP5
Protein YIP5

1

0

High-throughput

0.249

Low

916400

MCE1
mRNA-capping enzyme subunit alpha

1

0

High-throughput

0.249

Low

916402

RT24
Small ribosomal subunit protein mS35

1

0

High-throughput

0.249

Low

916403

PEX12
Peroxisome assembly protein 12

1

0

High-throughput

0.249

Low

916406

YD073
UPF0592 protein YDL073W

1

0

High-throughput

0.249

Low

916407

PGC1
Phosphatidylglycerol phospholipase C

1

0

High-throughput

0.249

Low

916411

RFM1
Repression factor of MSEs protein 1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025