Interactor 1: PYRE (P0CB78)
Orotate phosphoribosyltransferase (OPRT) (OPRTase) (EC 2.4.2.10)
Gene: PYRE

Interactor 2: PYRE (P0CB78)
Orotate phosphoribosyltransferase (OPRT) (OPRTase) (EC 2.4.2.10)
Gene: PYRE

Species: Streptococcus pneumoniae TIGR4

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 19098921
Identification Methods miniaturized immunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pribosyltran~Pribosyltran
Common GO terms GO:0000287 - magnesium ion binding
GO:0004588 - orotate phosphoribosyltransferase activity
GO:0004590 - orotidine-5'-phosphate decarboxylase activity
GO:0019856 - pyrimidine nucleobase biosynthetic process
GO:0044205 - 'de novo' UMP biosynthetic process
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 210
Sp

1 210
+ Hs
+ Ce
+ Sc
+ Sc
+ At
+ Ec
+ At
+ At
+ At
+ At
+ Cj
+ At
+ Sp
+ Cj

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024