HitPredict

Interactor 1: POTEI (P0CG38)
POTE ankyrin domain family member I
Gene: POTEI

Interactor 2: CDKL4 (Q5MAI5)
Cyclin-dependent kinase-like 4 (EC 2.7.11.22)
Gene: CDKL4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Actin~Pkinase, Ank_2~Pkinase
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1075 Hs			1 379
+	Hs
		625278 ACTB_HUMAN (701-1075): 0: 577: 91.20		CDK2_HUMAN (1-292): 3.58e-140: 402: 37.76
+	Hs
		625338 ACTG_HUMAN (701-1075): 0: 577: 90.67		CDK2_HUMAN (1-292): 3.58e-140: 402: 37.76
+	Hs
		625343 ACTS_HUMAN (699-1075): 0: 571: 85.68		CDK2_HUMAN (1-292): 3.58e-140: 402: 37.76
+	Hs
		891741 ACTB_HUMAN (701-1075): 0: 577: 91.20		MK07_HUMAN (2-365): 5.34e-131: 396: 24.80
+	Hs
		929843 ACTG_HUMAN (701-1075): 0: 577: 90.67		MK07_HUMAN (2-365): 5.34e-131: 396: 24.80
+	Hs
		841152 ACTG_HUMAN (701-1075): 0: 577: 90.67		CDK7_HUMAN (2-288): 1.63e-62: 205: 38.87
+	Hs
		841154 ACTC_HUMAN (699-1075): 0: 571: 86.21		CDK7_HUMAN (2-288): 1.63e-62: 205: 38.87
+	Hs
		841156 ACTS_HUMAN (699-1075): 0: 571: 85.68		CDK7_HUMAN (2-288): 1.63e-62: 205: 38.87