HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	25411243, 15710384
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, ubiquitination reaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005789 - endoplasmic reticulum membrane GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0031982 - vesicle and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 193
+	Hs
		475593 UBC_HUMAN (1-685): 0: 846: 100.00		RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22
+	Hs
		475625 UBC_HUMAN (1-685): 0: 846: 100.00		RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40
+	Hs
		475548 UBC_HUMAN (1-685): 0: 846: 100.00		CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33
+	Sc
		419667 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		RHO1_YEAST (3-188): 1.51e-97: 283: 73.12
+	Hs
		900357 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00
+	Hs
		923947 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22
+	Rn
		1144214 UBC_RAT (1-108): 1.27e-29: 127: 90.74		RAC1_RAT (1-193): 8.86e-80: 237: 57.22
+	Mm
		476750 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		RAC1_MOUSE (1-193): 8.86e-80: 237: 57.22
+	Rn
		1104200 UBC_RAT (1-108): 1.27e-29: 127: 90.74		Q32PX6_RAT (1-193): 2.83e-77: 231: 54.40
+	Rn
		1144234 UBC_RAT (1-108): 1.27e-29: 127: 90.74		CDC42_RAT (1-193): 5.51e-77: 230: 52.33
+	Rn
		916116 UBC_RAT (1-108): 1.27e-29: 127: 90.74		RHOB_RAT (1-191): 1.62e-73: 221: 83.94
+	Hs
		474987 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22
+	Hs
		474983 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94