HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: UBXN1 (Q04323)
UBX domain-containing protein 1 (SAPK substrate protein 1) (UBA/UBX 33.3 kDa protein)
Gene: UBXN1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.94	1.00	0.973

Property	Details
Experiments	18775313, 21135095, 15362974, 32039147, 20351172, 28190767, 31699778, 31494268, 38803224, 19285159
Identification Methods	affinity chromatography technology, pull down, unspecified method, protein array
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	UBA~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 685 Hs			1 297
+	Hs
		299310 UBC_HUMAN (1-685): 0: 846: 100.00		UBXN7_HUMAN (45-294): 2.33e-43: 156: 17.13
+	Hs
		476571 UBC_HUMAN (1-685): 0: 846: 100.00		FAF1_HUMAN (71-294): 1.76e-41: 153: 22.12
+	Hs
		476145 UBC_HUMAN (1-685): 0: 846: 100.00		UBP13_HUMAN (2-162): 3.18e-36: 139: 22.98
+	Hs
		475461 UBC_HUMAN (1-685): 0: 846: 100.00		UBP5_HUMAN (1-162): 6.44e-32: 127: 25.31
+	Hs
		476098 UBC_HUMAN (1-685): 0: 846: 100.00		UBS3B_HUMAN (5-73): 4.15e-16: 80.4: 46.38
+	At
		1091780 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		UBP14_ARATH (1-51): 5.02e-14: 74.3: 43.14
+	Mm
		476957 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		UBXN1_MOUSE (1-297): 3.84e-69: 218: 92.93
+	Hs
		397924 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		UBXN1_HUMAN (1-297): 5.45e-68: 215: 100.00
+	Mm
		476842 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		UBXN7_MOUSE (45-294): 2.81e-46: 163: 17.93
+	Mm
		476721 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		FAF1_MOUSE (71-294): 1.1e-40: 151: 22.12
+	Hs
		800571 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		UBP5_HUMAN (1-162): 6.44e-32: 127: 25.31
+	Rn
		1144247 UBC_RAT (1-108): 1.27e-29: 127: 90.74		FAF1_RAT (71-294): 7.51e-39: 146: 22.57
+	Mm
		476806 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		UBP13_MOUSE (2-162): 6.9e-38: 144: 22.36
+	Hs
		398140 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		FAF1_HUMAN (71-294): 1.76e-41: 153: 22.12
+	Rn
		88579 UBC_RAT (1-108): 1.27e-29: 127: 90.74		D3ZDI9_RAT (2-162): 6.32e-34: 132: 22.98
+	Mm
		476724 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		UBP5_MOUSE (1-162): 1.35e-32: 128: 25.93
+	Rn
		88803 UBC_RAT (1-108): 1.27e-29: 127: 90.74		D3ZVQ0_RAT (1-162): 1.62e-32: 128: 25.31
+	Hs
		397832 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		UBP5_HUMAN (1-162): 6.44e-32: 127: 25.31
+	Hs
		924089 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		UBS3B_HUMAN (5-73): 4.15e-16: 80.4: 46.38
+	Mm
		476878 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		UBS3B_MOUSE (5-73): 4.11e-16: 80.4: 46.38