HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: KPCZ (Q05513)
Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)
Gene: PRKCZ

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	38803224
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Pkinase~ubiquitin
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0031982 - vesicle GO:0070062 - extracellular exosome
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 592
+	Hs
		475450 UBC_HUMAN (1-685): 0: 846: 100.00		KPCI_HUMAN (1-592): 0: 654: 69.87
+	Hs
		475390 UBC_HUMAN (1-685): 0: 846: 100.00		AKT1_HUMAN (172-582): 1.55e-153: 451: 36.39
+	Hs
		475345 UBC_HUMAN (1-685): 0: 846: 100.00		KS6B1_HUMAN (227-590): 1.48e-144: 430: 35.60
+	Hs
		116959 UBC_HUMAN (1-685): 0: 846: 100.00		SGK1_HUMAN (199-583): 7.41e-144: 424: 38.36
+	Hs
		408535 UBC_HUMAN (1-685): 0: 846: 100.00		KPCB_HUMAN (85-187): 1.04e-21: 101: 27.18
+	Hs
		475314 UBC_HUMAN (1-685): 0: 846: 100.00		KPCA_HUMAN (101-181): 1.39e-16: 85.3: 29.63
+	Mm
		476830 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		KPCI_MOUSE (1-592): 0: 655: 69.70
+	Rn
		448410 UBC_RAT (1-108): 1.27e-29: 127: 90.74		KPCD_RAT (63-583): 3.17e-180: 526: 34.48
+	Hs
		681773 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		AKT1_HUMAN (172-582): 1.55e-153: 451: 36.39
+	Hs
		474936 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		AKT2_HUMAN (148-582): 5.85e-155: 455: 36.12
+	Hs
		474935 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		AKT1_HUMAN (172-582): 1.55e-153: 451: 36.39
+	Hs
		923962 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		KPCE_HUMAN (6-196): 1.52e-27: 120: 19.02
+	Rn
		448416 UBC_RAT (1-108): 1.27e-29: 127: 90.74		KPCE_RAT (6-190): 3.1e-27: 118: 18.91
+	Rn
		934619 UBC_RAT (1-108): 1.27e-29: 127: 90.74		KPCB_RAT (101-181): 2.68e-17: 87.6: 30.86
+	Hs
		408534 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		KPCB_HUMAN (85-187): 1.04e-21: 101: 27.18
+	Rn
		930581 UBC_RAT (1-108): 1.27e-29: 127: 90.74		KPCG_RAT (116-180): 1.79e-10: 65.9: 36.92