Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: OTU7B (Q6GQQ9)
OTU domain-containing protein 7B (EC 3.4.19.12) (Cellular zinc finger anti-NF-kappa-B protein) (Cezanne) (Zinc finger A20 domain-containing protein 1) (Zinc finger protein Cezanne)
Gene: OTUD7B

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.983

The method score is based on:

Property Details
Experiments 29576527, 27182664, 31699778, 31937588, 33141564, 34642328, 38803224, 22179831, 25752577, 25723849, 26876099, 27732584, 20622874, 23827681
Identification Methods pull down, proximity labelling technology, affinity chromatography technology, enzymatic study, x-ray crystallography
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains OTU~ubiquitin, UBA_4~ubiquitin, ubiquitin~zf-A20
Common GO terms GO:0005634 - nucleus
GO:0005829 - cytosol
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 685
Hs

1 843
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Dm
+ Dr
+ Mm
+ Hs
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024