Protein: GNAZ
Guanine nucleotide-binding protein G(z) subunit alpha (G(x) alpha chain) (Gz-alpha)

Gene: GNAZ
Organism: Homo sapiens
Interactions: 82
UniProt ID: P19086

Gene Ontology (top 5):
GO:0001664 - G protein-coupled receptor binding
GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005635 - nuclear envelope
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

618468

P2RY8
S-geranylgeranyl-glutathione receptor P2RY8

3

19

High-throughput

0.861

High

618455

DMWD
Dystrophia myotonica WD repeat-containing protein

2

4

High-throughput

0.811

High

303104

RGS20
Regulator of G-protein signaling 20

2

20

Small-scale

0.778

High

618463

DCA10
DDB1- and CUL4-associated factor 10

3

8

High-throughput

0.770

High

618441

RGS19
Regulator of G-protein signaling 19

2

20

Small-scale

0.754

High

618432

GNAZ
Guanine nucleotide-binding protein G(z) subunit alpha

1

13

High-throughput

0.698

High

618486

RIC8A
Chaperone Ric-8A

1

13

High-throughput

0.691

High

618446

EPHA4
Ephrin type-A receptor 4

3

7

High-throughput

0.667

High

618472

T185A
Transmembrane protein 185A

3

3

High-throughput

0.667

High

618495

DAAM1
Disheveled-associated activator of morphogenesis 1

3

1

High-throughput

0.667

High

618475

FBXW5
F-box/WD repeat-containing protein 5

1

0

High-throughput

0.656

High

618433

DRD5
D(1B) dopamine receptor

1

11

Small-scale

0.647

High

618439

RPGP1
Rap1 GTPase-activating protein 1

1

4

Small-scale

0.647

High

618452

GBG3

2

20

High-throughput

0.628

High

618458

BIRC2
Baculoviral IAP repeat-containing protein 2

2

2

High-throughput

0.628

High

618493

PCDGK
Protocadherin gamma-C3

2

1

High-throughput

0.628

High

223464

RGS10
Regulator of G-protein signaling 10

1

20

Small-scale

0.618

High

239449

AGRB2
Adhesion G protein-coupled receptor B2

1

3

Small-scale

0.618

High

618442

RGS7
Regulator of G-protein signaling 7

1

20

Small-scale

0.618

High

618464

RN123
E3 ubiquitin-protein ligase RNF123

2

1

High-throughput

0.611

High

478656

HXB5
Homeobox protein Hox-B5

3

4

High-throughput

0.609

High

618437

MTHR
Methylenetetrahydrofolate reductase

3

1

High-throughput

0.609

High

618470

S2541
Mitochondrial carrier protein SCaMC-3L

3

3

High-throughput

0.609

High

618489

NUFP1
FMR1-interacting protein NUFIP1

3

3

High-throughput

0.609

High

618461

LRRK1
Leucine-rich repeat serine/threonine-protein kinase 1

2

4

High-throughput

0.602

High

618459

MED21
Mediator of RNA polymerase II transcription subunit 21

2

1

High-throughput

0.574

High

618466

CXB7
Gap junction beta-7 protein

2

3

High-throughput

0.574

High

618480

UIF
UAP56-interacting factor

2

3

High-throughput

0.558

High

618481

CCNL2
Cyclin-L2

2

2

High-throughput

0.558

High

563161

CFTR
Cystic fibrosis transmembrane conductance regulator

1

4

High-throughput

0.541

High

560302

IFM1
Interferon-induced transmembrane protein 1

1

5

High-throughput

0.536

High

618443

GBG10

1

20

High-throughput

0.536

High

618444

GPM6A
Neuronal membrane glycoprotein M6-a

1

2

High-throughput

0.536

High

618449

GBG2
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2

1

20

High-throughput

0.536

High

618451

GBG1
Guanine nucleotide-binding protein G(T) subunit gamma-T1

1

20

High-throughput

0.536

High

618453

HBG2
Hemoglobin subunit gamma-2

1

2

High-throughput

0.536

High

618467

RD3
Protein RD3

1

2

High-throughput

0.536

High

618476

ISG20
Interferon-stimulated gene 20 kDa protein

1

3

High-throughput

0.536

High

618478

CERS2
Ceramide synthase 2

1

3

High-throughput

0.536

High

618491

GBG8
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8

1

20

High-throughput

0.536

High

287434

RPC9
DNA-directed RNA polymerase III subunit RPC9

1

0

High-throughput

0.513

High

300104

GLRX3
Glutaredoxin-3

1

0

High-throughput

0.513

High

616714

SDC1
Syndecan-1

1

0

High-throughput

0.513

High

618492

DD19B
ATP-dependent RNA helicase DDX19B

1

0

High-throughput

0.513

High

421469

A4
Amyloid-beta precursor protein

1

5

High-throughput

0.501

High

618454

CXCL6
C-X-C motif chemokine 6

1

1

High-throughput

0.489

High

124577

EYA2
Protein phosphatase EYA2

1

5

Small-scale

0.481

High

240710

PRKN
E3 ubiquitin-protein ligase parkin

1

4

High-throughput

0.479

High

618434

SYVC
Valine--tRNA ligase

1

2

High-throughput

0.479

High

618438

YAP1
Transcriptional coactivator YAP1

1

11

High-throughput

0.479

High

618440

SOX2
Transcription factor SOX-2

1

3

High-throughput

0.479

High

618445

GDS1
Rap1 GTPase-GDP dissociation stimulator 1

1

2

High-throughput

0.479

High

618448

MLF1
Myeloid leukemia factor 1

1

5

High-throughput

0.479

High

618450

ABCE1
ATP-binding cassette sub-family E member 1

1

2

High-throughput

0.479

High

618460

MLF2
Myeloid leukemia factor 2

1

5

High-throughput

0.479

High

618462

TBB8
Tubulin beta-8 chain

1

3

High-throughput

0.479

High

618474

VPP1
V-type proton ATPase 116 kDa subunit a 1

1

1

High-throughput

0.479

High

618483

AASD1
Alanyl-tRNA editing protein Aarsd1

1

4

High-throughput

0.479

High

618485

CYBP
Calcyclin-binding protein

1

2

High-throughput

0.479

High

618465

THOC7
THO complex subunit 7

1

0

High-throughput

0.458

High

618469

NUDC3
NudC domain-containing protein 3

1

0

High-throughput

0.458

High

254794

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

8

High-throughput

0.445

High

529044

TAU
Microtubule-associated protein tau

1

16

High-throughput

0.445

High

618436

HD
Huntingtin

1

11

High-throughput

0.445

High

618447

TERA
Transitional endoplasmic reticulum ATPase

1

6

High-throughput

0.445

High

618479

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

14

High-throughput

0.445

High

618494

ITM2B
Integral membrane protein 2B

1

8

High-throughput

0.445

High

105300

APRIO
Alternative prion protein

1

6

High-throughput

0.437

High

618435

STIP1
Stress-induced-phosphoprotein 1

1

2

High-throughput

0.437

High

618456

TFCP2
Alpha-globin transcription factor CP2

1

8

High-throughput

0.437

High

618457

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

1

High-throughput

0.437

High

618477

Q96BE0
Heat shock cognate 71 kDa protein

1

7

High-throughput

0.437

High

618490

FKBPL
FK506-binding protein-like

1

3

High-throughput

0.437

High

618471

ACBD7
Acyl-CoA-binding domain-containing protein 7

2

0

High-throughput

0.328

High

71288

F1712
Protein FAM171A2

2

0

High-throughput

0.318

High

618473

GLMP
Glycosylated lysosomal membrane protein

2

0

High-throughput

0.318

High

618482

APOL2
Apolipoprotein L2

2

0

High-throughput

0.318

High

555202

ECP
Eosinophil cationic protein

1

0

High-throughput

0.279

Low

618487

CENPM
Centromere protein M

1

0

High-throughput

0.279

Low

618488

SPG21
Maspardin

1

0

High-throughput

0.279

Low

618484

TM6S2
Transmembrane 6 superfamily member 2

1

0

High-throughput

0.269

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025