Protein: GNAO
G protein alpha o subunit (Guanine nucleotide-binding protein G(o) subunit alpha 47A)

Gene: GNAO, Galphao
Organism: Drosophila melanogaster
Interactions: 32
UniProt ID: P16378

Gene Ontology (top 5):
GO:0001664 - G protein-coupled receptor binding
GO:0001737 - establishment of imaginal disc-derived wing hair orientation
GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

594797

Q9VB22
LD33695p

8

13

Small-scale

0.969

High

594799

RGS
Regulator of G-protein signaling loco

2

20

Small-scale

0.807

High

68583

A8JNM5
Ankyrin 2, isoform K

1

2

Small-scale

0.713

High

594792

Q8T017
Double hit, isoform B

1

20

Small-scale

0.662

High

121732

M9PGB1
Rho-type guanine nucleotide exchange factor, isoform G

1

4

High-throughput

0.621

High

594807

Q9VM00
Rap GTPase activating protein 1, isoform D

1

4

Small-scale

0.621

High

594794

GUTR1
Protein trapped in endoderm-1

1

17

Small-scale

0.618

High

594796

AXN
Axin

1

20

Small-scale

0.618

High

594795

RAB5
Ras-related protein Rab5

2

5

Small-scale

0.600

High

594803

Q9VIN1
Rho-type guanine nucleotide exchange factor, isoform A

1

3

High-throughput

0.590

High

594784

GBB1
Guanine nucleotide-binding protein subunit beta-1

2

20

Small-scale

0.571

High

594804

Q9VJ57
Grip71

1

3

High-throughput

0.508

High

594806

Q9VK21
Kelch-like protein diablo

1

0

High-throughput

0.486

High

594811

VA0D1
V-type proton ATPase subunit d 1

1

0

High-throughput

0.486

High

594785

BIP
Endoplasmic reticulum chaperone BiP

1

7

Small-scale

0.479

High

594788

TBB1
Tubulin beta-1 chain

1

3

Small-scale

0.479

High

594790

Q7KY04
small monomeric GTPase

1

5

Small-scale

0.479

High

594800

MTH5
Probable G-protein coupled receptor Mth-like 5

1

9

Small-scale

0.479

High

594810

Q9W2R4
Inscuteable

1

1

Small-scale

0.479

High

559700

KNRL
Knirps-related protein

1

7

High-throughput

0.464

High

594798

Q9VC60
BUD13 homolog

1

4

High-throughput

0.464

High

52300

A1Z6R7
FI21445p1

1

4

High-throughput

0.457

High

594791

Q86LC4
Gamma-tubulin ring complex subunit Dgrip71

1

3

High-throughput

0.457

High

594801

Q9VH66
FI18258p1

1

8

High-throughput

0.457

High

594786

GBG1
Guanine nucleotide-binding protein subunit gamma-1

1

20

High-throughput

0.445

High

594809

Q9VWL9
LD25711p

1

0

High-throughput

0.426

High

594787

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.265

Low

594805

Q9VJX7
AT04835p

1

0

High-throughput

0.265

Low

594808

Q9VME5
Slow as molasses, isoform B

1

0

High-throughput

0.265

Low

594789

Q7JX82
GH21964p

1

0

Small-scale

0.249

Low

594793

Q8T9G7
SD01558p

1

0

High-throughput

0.238

Low

594802

Q9VHK9
RH02303p

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025