HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: RN166 (Q96A37)
E3 ubiquitin-protein ligase RNF166 (EC 2.3.2.27) (RING finger protein 166) (RING-type E3 ubiquitin transferase RNF166)
Gene: RNF166

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.80	0.579

Property	Details
Experiments	38803224
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	ubiquitin~zf-RING_UBOX
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 685 Hs			1 237
+	Hs
		476632 UBC_HUMAN (1-685): 0: 846: 100.00		RN114_HUMAN (18-236): 1.44e-49: 163: 46.12
+	Hs
		476111 UBC_HUMAN (1-685): 0: 846: 100.00		RN138_HUMAN (21-237): 4.61e-45: 152: 30.83
+	Hs
		476188 UBC_HUMAN (1-685): 0: 846: 100.00		RN125_HUMAN (6-236): 1.1e-41: 143: 30.67
+	Hs
		475680 UBC_HUMAN (1-685): 0: 846: 100.00		TRI26_HUMAN (19-174): 1.05e-34: 131: 18.24
+	Hs
		129527 UBC_HUMAN (1-685): 0: 846: 100.00		TRAF5_HUMAN (12-237): 8.71e-31: 120: 21.21
+	Hs
		475328 UBC_HUMAN (1-685): 0: 846: 100.00		RO52_HUMAN (19-166): 8.73e-31: 120: 20.95
+	Hs
		475309 UBC_HUMAN (1-685): 0: 846: 100.00		RAG1_HUMAN (30-149): 1.21e-28: 115: 28.23
+	Hs
		476627 UBC_HUMAN (1-685): 0: 846: 100.00		TRAF6_HUMAN (8-235): 8.66e-29: 114: 17.83
+	Hs
		476299 UBC_HUMAN (1-685): 0: 846: 100.00		TRAF4_HUMAN (17-212): 3.54e-28: 112: 18.50
+	Hs
		475684 UBC_HUMAN (1-685): 0: 846: 100.00		TRAF2_HUMAN (15-186): 9.47e-27: 109: 20.65
+	Hs
		476330 UBC_HUMAN (1-685): 0: 846: 100.00		TRIM5_HUMAN (21-166): 6.19e-25: 103: 20.53
+	Hs
		476635 UBC_HUMAN (1-685): 0: 846: 100.00		TRI17_HUMAN (25-167): 3.15e-24: 101: 18.83
+	Hs
		475842 UBC_HUMAN (1-685): 0: 846: 100.00		RN151_HUMAN (24-172): 3.71e-22: 93: 24.05
+	Hs
		476489 UBC_HUMAN (1-685): 0: 846: 100.00		KCMF1_HUMAN (143-213): 4.51e-21: 92.2: 33.80
+	Xl
		1186351 Q7SY79_XENLA (77-685): 0: 744: 99.84		NF7B_XENLA (5-165): 3.18e-27: 111: 18.52
+	Mm
		476671 UBB_MOUSE (457-685): 2.3e-86: 275: 99.56		RO52_MOUSE (15-165): 5.11e-31: 120: 18.54
+	At
		1092004 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		SM3L1_ARATH (29-84): 6.24e-11: 63.6: 35.71
+	Mm
		924236 RS27A_MOUSE (609-684): 9.1e-41: 147: 100.00		RO52_MOUSE (15-165): 5.11e-31: 120: 18.54
+	Hs
		924227 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		TRAF6_HUMAN (8-235): 8.66e-29: 114: 17.83
+	Hs
		924151 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		TRI31_HUMAN (19-180): 1.72e-25: 104: 15.85