HitPredict

Interactor 1: A0AR23 (A0AR23)
RING-type E3 ubiquitin transferase (EC 2.3.2.27)
Gene: mib2

Interactor 2: HIF1N (P59723)
Hypoxia-inducible factor 1-alpha inhibitor (EC 1.14.11.30) (EC 1.14.11.n4) (Hypoxia-inducible factor asparagine hydroxylase)
Gene: hif1an

Species: Danio rerio

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24714733
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank~Cupin_8
Common GO terms	GO:0005737 - cytoplasm GO:0008270 - zinc ion binding GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 999 Dr			1 344
+	Hs
		1284696 MIB2_HUMAN (48-999): 0: 694: 60.83		HIF1N_HUMAN (10-340): 2.84e-131: 380: 83.38
+	Hs
		1021468 ANK3_HUMAN (482-973): 2.21e-121: 412: 18.89		HIF1N_HUMAN (10-340): 2.84e-131: 380: 83.38
+	Hs
		167023 ANR28_HUMAN (251-889): 1.68e-124: 406: 16.29		HIF1N_HUMAN (10-340): 2.84e-131: 380: 83.38
+	Hs
		965164 ANK2_HUMAN (473-994): 1.39e-119: 406: 19.33		HIF1N_HUMAN (10-340): 2.84e-131: 380: 83.38
+	Hs
		1239510 ANR52_HUMAN (288-875): 5.54e-119: 392: 17.18		HIF1N_HUMAN (10-340): 2.84e-131: 380: 83.38
+	Hs
		1329536 TNKS2_HUMAN (481-979): 5.68e-98: 336: 16.33		HIF1N_HUMAN (10-340): 2.84e-131: 380: 83.38
+	Dr
		887090 MIB1_DANRE (42-718): 7.58e-82: 288: 19.55		HIF1N_DANRE (1-344): 1.56e-139: 401: 100.00
+	Hs
		1237555 ANR44_HUMAN (579-969): 2.6e-71: 258: 17.14		HIF1N_HUMAN (10-340): 2.84e-131: 380: 83.38
+	Hs
		1347414 KDIS_HUMAN (304-682): 2.56e-62: 233: 19.74		HIF1N_HUMAN (10-340): 2.84e-131: 380: 83.38
+	Hs
		1219860 ANKH1_HUMAN (601-993): 2.65e-57: 218: 13.28		HIF1N_HUMAN (10-340): 2.84e-131: 380: 83.38
+	Hs
		310099 TNKS1_HUMAN (715-985): 1.39e-51: 199: 14.84		HIF1N_HUMAN (10-340): 2.84e-131: 380: 83.38
+	Hs
		1244264 ANKK1_HUMAN (638-929): 4.67e-50: 192: 14.65		HIF1N_HUMAN (10-340): 2.84e-131: 380: 83.38
+	Hs
		1347416 ANR50_HUMAN (210-473): 2.04e-33: 142: 9.64		HIF1N_HUMAN (10-340): 2.84e-131: 380: 83.38
+	Hs
		1330861 Q9H4D1_HUMAN (392-595): 1.07e-29: 129: 23.53		HIF1N_HUMAN (10-340): 2.84e-131: 380: 83.38
+	Hs
		883653 RIPK4_HUMAN (392-595): 1.25e-29: 129: 23.53		HIF1N_HUMAN (10-340): 2.84e-131: 380: 83.38
+	Hs
		1302643 Q96T11_HUMAN (442-856): 1.36e-24: 112: 28.81		HIF1N_HUMAN (10-340): 2.84e-131: 380: 83.38
+	Hs
		1347428 INVS_HUMAN (304-464): 4.06e-12: 72.5: 8.70		HIF1N_HUMAN (10-340): 2.84e-131: 380: 83.38
+	Hs
		257711 ANR17_HUMAN (230-362): 3.16e-11: 70.1: 10.87		HIF1N_HUMAN (10-340): 2.84e-131: 380: 83.38
+	Hs
		1334134 EHMT1_HUMAN (377-523): 6.1e-11: 68.9: 17.96		HIF1N_HUMAN (10-340): 2.84e-131: 380: 83.38