Interactor 1: IL6RA (P08887)
Interleukin-6 receptor subunit alpha (IL-6 receptor subunit alpha) (IL-6R subunit alpha) (IL-6R-alpha) (IL-6RA) (IL-6R 1) (Membrane glycoprotein 80) (gp80) (CD antigen CD126) [Cleaved into: Soluble interleukin-6 receptor subunit alpha (sIL6R)]
Gene: IL6R
Interactor 2: CNTF (P26441)
Ciliary neurotrophic factor (CNTF)
Gene: CNTF
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.66 | 1.00 | 0.812 |
The method score is based on:
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CNTF~IL6Ra-bind |
| Common GO terms | GO:0005576 - extracellular region GO:0005615 - extracellular space GO:0008284 - positive regulation of cell population proliferation GO:0070120 - ciliary neurotrophic factor-mediated signaling pathway GO:0097696 - cell surface receptor signaling pathway via STAT |
| Homologous interactions | 6 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
