HitPredict

Interactor 1: UBI4P (P0CG63)
Polyubiquitin [Cleaved into: Ubiquitin]
Gene: UBI4

Interactor 2: UBC1 (P21734)
Ubiquitin-conjugating enzyme E2 1 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 1) (Ubiquitin carrier protein) (Ubiquitin-conjugating enzyme E2-24 kDa) (Ubiquitin-protein ligase)
Gene: UBC1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.94	1.00	0.970

Property	Details
Experiments	2065660, 15328341, 18662542, 26142280, 33576509, 16014632, 19620964, 2265617
Identification Methods	pull down, enzymatic study, x-ray crystallography
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	UQ_con~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 381 Sc			1 215
+	Sc
		477103 UBI4P_YEAST (1-381): 4.37e-161: 458: 100.00		UBC4_YEAST (1-149): 9.98e-77: 229: 44.97
+	Dr
		94560 F1QHN6_DANRE (1-380): 1.46e-163: 470: 96.05		Q7T3F3_DANRE (4-149): 8.25e-69: 209: 41.10
+	Rn
		88580 UBC_RAT (1-333): 8.71e-131: 395: 93.99		UB2D1_RAT (2-150): 2.39e-76: 227: 44.97
+	Mm
		476737 UBC_MOUSE (1-333): 9.24e-132: 396: 93.99		UB2D3_MOUSE (2-150): 2.28e-75: 225: 43.62
+	Mm
		476739 UBC_MOUSE (1-333): 9.24e-132: 396: 93.99		UBE2N_MOUSE (4-150): 1.64e-69: 210: 41.50
+	Rn
		1144263 UBC_RAT (1-333): 8.71e-131: 395: 93.99		UBE2N_RAT (4-150): 3.33e-69: 210: 41.50
+	At
		1091932 UBQ3_ARATH (77-381): 2.59e-125: 365: 97.05		UBC28_ARATH (2-151): 3.45e-77: 230: 45.33
+	At
		715116 UBQ3_ARATH (77-381): 2.59e-125: 365: 97.05		UBC8_ARATH (2-151): 1.08e-76: 229: 46.00
+	At
		715132 UBQ3_ARATH (77-381): 2.59e-125: 365: 97.05		UBC9_ARATH (2-151): 2.95e-76: 227: 45.33
+	At
		715147 UBQ3_ARATH (77-381): 2.59e-125: 365: 97.05		UBC10_ARATH (2-151): 4.19e-76: 227: 45.33
+	At
		715157 UBQ3_ARATH (77-381): 2.59e-125: 365: 97.05		UBC11_ARATH (2-151): 3.4e-76: 227: 47.33
+	At
		1092090 UBQ3_ARATH (77-381): 2.59e-125: 365: 97.05		UBC36_ARATH (2-152): 2.6e-68: 207: 43.05
+	At
		1092025 UBQ3_ARATH (77-381): 2.59e-125: 365: 97.05		UBC27_ARATH (1-193): 1e-65: 202: 45.36
+	At
		639385 UBQ3_ARATH (77-381): 2.59e-125: 365: 97.05		UBC1_ARATH (1-147): 8.85e-65: 199: 34.23
+	At
		790155 UBQ3_ARATH (77-381): 2.59e-125: 365: 97.05		UBC2_ARATH (1-147): 6.38e-65: 199: 33.56
+	Mm
		476738 UBC_MOUSE (1-333): 9.24e-132: 396: 93.99		UBE2K_MOUSE (1-149): 6.1e-42: 142: 50.34
+	Xl
		919927 Q7SY79_XENLA (1-229): 7.03e-88: 279: 95.63		UB2D2_XENLA (2-150): 1.55e-76: 228: 44.97
+	Dm
		639414 Q9W418_DROME (1-230): 6.72e-89: 279: 95.22		UBCD1_DROME (2-150): 4e-76: 227: 46.98
+	Hs
		1137415 Q5U5U6_HUMAN (77-304): 5.9e-91: 274: 96.05		UB2E3_HUMAN (2-150): 5.53e-69: 211: 42.95
+	Hs
		474958 UBB_HUMAN (77-304): 5.9e-91: 274: 96.05		UBE2A_HUMAN (1-147): 5.72e-65: 199: 37.58