Interactor 1: ACM5 (P08912)
Muscarinic acetylcholine receptor M5
Gene: CHRM5
Interactor 2: M3K1 (Q13233)
Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1) (EC 2.3.2.27)
Gene: MAP3K1
Species: Homo sapiens
Source: mint
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.48 | 0.80 | 0.625 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 28298427 |
| Identification Methods | two hybrid, ubiquitin reconstruction |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | 7tm_1~Pkinase |
| Common GO terms | - |
| Homologous interactions | 4 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
