Protein: DRD1
D(1A) dopamine receptor (Dopamine D1 receptor)

Gene: DRD1
Organism: Homo sapiens
Interactions: 21
UniProt ID: P21728

Gene Ontology (top 5):
GO:0001588 - dopamine neurotransmitter receptor activity, coupled via Gs
GO:0001659 - temperature homeostasis
GO:0001661 - conditioned taste aversion
GO:0001662 - behavioral fear response
GO:0001965 - G-protein alpha-subunit binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

640348

DRD3
D(3) dopamine receptor

1

18

Small-scale

0.724

High

640347

AA1R
Adenosine receptor A1

1

15

Small-scale

0.665

High

603160

KPCA
Protein kinase C alpha type

1

2

High-throughput

0.665

High

605547

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

1

Small-scale

0.647

High

640358

GHSR
Growth hormone secretagogue receptor type 1

1

17

Small-scale

0.647

High

640363

HRH3
Histamine H3 receptor

1

18

Small-scale

0.647

High

640350

DLG4
Disks large homolog 4

1

15

Small-scale

0.561

High

640360

VPS35
Vacuolar protein sorting-associated protein 35

1

1

Small-scale

0.561

High

640362

COPG2
Coatomer subunit gamma-2

1

4

Small-scale

0.561

High

640364

COPG1
Coatomer subunit gamma-1

1

4

Small-scale

0.561

High

640355

DJC14
DnaJ homolog subfamily C member 14

1

3

Small-scale

0.527

High

640349

1433G
14-3-3 protein gamma

1

4

High-throughput

0.515

High

640352

SETB1
Histone-lysine N-methyltransferase SETDB1

1

1

High-throughput

0.515

High

163410

MEIS2
Homeobox protein Meis2

1

1

Small-scale

0.501

High

640353

TGIF1
Homeobox protein TGIF1

1

1

Small-scale

0.501

High

640356

LMO3
LIM domain only protein 3

1

0

High-throughput

0.493

High

640359

KAT5
Histone acetyltransferase KAT5

1

0

High-throughput

0.493

High

640357

PDC6I
Programmed cell death 6-interacting protein

1

3

Small-scale

0.481

High

640351

CRFR2
Corticotropin-releasing factor receptor 2

1

3

Small-scale

0.479

High

640354

RBP10
Ran-binding protein 10

1

7

Small-scale

0.479

High

640361

RANB9
Ran-binding protein 9

1

7

Small-scale

0.479

High


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Last updated: 11Aug2025