Protein: PAPS1
Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 (PAPS synthase 1) (PAPSS 1) (Sulfurylase kinase 1) (SK 1) (SK1) [Includes: Sulfate adenylyltransferase (EC 2.7.7.4) (ATP-sulfurylase) (Sulfate adenylate transferase) (SAT); Adenylyl-sulfate kinase (EC 2.7.1.25) (3'-phosphoadenosine-5'-phosphosulfate synthase) (APS kinase) (Adenosine-5'-phosphosulfate 3'-phosphotransferase) (Adenylylsulfate 3'-phosphotransferase)]

Gene: PAPS1, PAPSS1
Organism: Homo sapiens
Interactions: 45
UniProt ID: O43252

Gene Ontology (top 5):
GO:0000103 - sulfate assimilation
GO:0001501 - skeletal system development
GO:0004020 - adenylylsulfate kinase activity
GO:0004781 - sulfate adenylyltransferase (ATP) activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

199028

PAPS2
Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2

2

7

High-throughput

0.802

High

174327

FANCG
Fanconi anemia group G protein

2

0

High-throughput

0.602

High

199044

DC1I2
Cytoplasmic dynein 1 intermediate chain 2

2

0

High-throughput

0.602

High

199025

PRKN
E3 ubiquitin-protein ligase parkin

2

5

High-throughput

0.584

High

199042

KPCE
Protein kinase C epsilon type

2

0

High-throughput

0.547

High

199034

PRPS2
Ribose-phosphate pyrophosphokinase 2

1

1

High-throughput

0.536

High

199040

IMA5
Importin subunit alpha-5

1

1

High-throughput

0.536

High

199041

EF1A1
Elongation factor 1-alpha 1

1

0

High-throughput

0.518

High

199045

U119A
Protein unc-119 homolog A

1

0

High-throughput

0.518

High

199027

RNH2A
Ribonuclease H2 subunit A

1

0

High-throughput

0.513

High

199029

ASML
Probable bifunctional dTTP/UTP pyrophosphatase/methyltransferase protein [Includes: dTTP/UTP pyrophosphatase

1

0

High-throughput

0.513

High

199035

NCK1
SH2/SH3 adapter protein NCK1

1

0

High-throughput

0.513

High

199036

RL35A
Large ribosomal subunit protein eL33

1

0

High-throughput

0.513

High

199043

TFCP2
Alpha-globin transcription factor CP2

1

0

High-throughput

0.513

High

199049

T132A
Transmembrane protein 132A

1

0

High-throughput

0.513

High

199056

FBLI1
Filamin-binding LIM protein 1

1

0

High-throughput

0.513

High

199066

FANCI
Fanconi anemia group I protein

1

0

High-throughput

0.513

High

199060

PP16A
Protein phosphatase 1 regulatory subunit 16A

1

1

High-throughput

0.494

High

199033

PARP1
Poly [ADP-ribose] polymerase 1

1

1

High-throughput

0.479

High

199059

FBXW7
F-box/WD repeat-containing protein 7

1

3

High-throughput

0.479

High

199068

ERRFI
ERBB receptor feedback inhibitor 1

1

0

Small-scale

0.460

High

199032

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.458

High

199052

YAF2
YY1-associated factor 2

1

0

High-throughput

0.458

High

199055

NHLC2
NHL repeat-containing protein 2

1

0

High-throughput

0.458

High

199063

TOLIP
Toll-interacting protein

1

0

High-throughput

0.458

High

199067

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

199050

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

2

High-throughput

0.445

High

199030

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

1

High-throughput

0.437

High

199037

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

199058

HDAC2
Histone deacetylase 2

1

1

High-throughput

0.437

High

199031

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

2

0

High-throughput

0.328

High

199039

GNL1
Guanine nucleotide-binding protein-like 1

2

0

High-throughput

0.328

High

199048

ODAPH
Odontogenesis associated phosphoprotein

2

0

High-throughput

0.328

High

199053

CC116
Coiled-coil domain-containing protein 116

2

0

High-throughput

0.328

High

199057

SNR27
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein

2

0

High-throughput

0.328

High

199061

GPX7
Glutathione peroxidase 7

2

0

High-throughput

0.328

High

199065

WDCP
WD repeat and coiled-coil-containing protein

2

0

High-throughput

0.328

High

199047

GALT3
Polypeptide N-acetylgalactosaminyltransferase 3

1

0

High-throughput

0.279

Low

199054

FA24B
Protein FAM24B

1

0

High-throughput

0.279

Low

199062

MCRI2
MAPK regulated corepressor interacting protein 2

1

0

High-throughput

0.279

Low

199064

SMOC1
SPARC-related modular calcium-binding protein 1

1

0

High-throughput

0.279

Low

199026

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.249

Low

199038

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

199051

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

199046

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024