HitPredict

Interactor 1: UBI4P (P0CG63)
Polyubiquitin [Cleaved into: Ubiquitin]
Gene: UBI4

Interactor 2: DOA1 (P36037)
Protein DOA1 (Degradation of alpha protein 1) (Ubiquitin fusion degradation protein 3)
Gene: DOA1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.95	1.00	0.977

Property	Details
Experiments	26349035, 16705165, 16427015, 28525741, 16428438, 21070969, 18508771, 38803224, 15096053
Identification Methods	affinity chromatography technology, two hybrid, pull down, x-ray crystallography
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	PFU~ubiquitin
Common GO terms	GO:0005634 - nucleus
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 381 Sc			1 715
+	Mm
		476692 UBC_MOUSE (1-333): 9.24e-132: 396: 93.99		PLAP_MOUSE (2-702): 1.92e-135: 419: 29.92
+	Sc
		408327 RS31_YEAST (305-380): 1.88e-41: 144: 100.00		DOA1_YEAST (1-715): 0: 540: 100.00
+	Hs
		476589 UBC_HUMAN (1-153): 1.84e-50: 181: 95.43		PLAP_HUMAN (2-702): 3.35e-135: 419: 29.56
+	Sc
		477239 UBI4P_YEAST (1-381): 4.37e-161: 458: 100.00		TAF5_YEAST (89-302): 5.91e-19: 93.6: 32.74
+	Dm
		477542 UBIQP_DROME (1-306): 2.48e-124: 377: 95.75		FBXW7_DROME (4-161): 8.39e-29: 125: 21.89
+	At
		1092114 UBQ3_ARATH (77-381): 2.59e-125: 365: 97.05		Q9LHN3_ARATH (206-552): 1.43e-30: 130: 10.57
+	Rn
		925834 UBC_RAT (1-333): 8.71e-131: 395: 93.99		LIS1_RAT (321-592): 9.59e-21: 97.4: 8.56
+	Mm
		476899 UBC_MOUSE (1-333): 9.24e-132: 396: 93.99		TBL3_MOUSE (100-320): 6.28e-09: 61.2: 22.41
+	Hs
		476547 UBC_HUMAN (1-153): 1.84e-50: 181: 95.43		FBW1B_HUMAN (99-329): 3.03e-45: 171: 23.53
+	Hs
		476595 UBC_HUMAN (1-153): 1.84e-50: 181: 95.43		FBW1A_HUMAN (124-459): 4.96e-44: 169: 15.79
+	Hs
		476151 UBC_HUMAN (1-153): 1.84e-50: 181: 95.43		FBXW7_HUMAN (205-534): 1.17e-40: 160: 14.63
+	Hs
		476181 UBC_HUMAN (1-153): 1.84e-50: 181: 95.43		SNR40_HUMAN (4-83): 2.88e-13: 73.9: 15.29
+	Hs
		475563 UBC_HUMAN (1-153): 1.84e-50: 181: 95.43		WDR5_HUMAN (2-82): 7.4e-13: 72.3: 12.64
+	Sc
		408338 RS31_YEAST (305-380): 1.88e-41: 144: 100.00		TAF5_YEAST (89-302): 5.91e-19: 93.6: 32.74
+	Hs
		397828 ISG15_HUMAN (3-152): 9.45e-31: 117: 32.68		LIS1_HUMAN (321-592): 1.05e-20: 97: 8.56
+	Hs
		903105 RS27A_HUMAN (77-153): 8.44e-20: 87: 94.81		WDR5_HUMAN (2-82): 7.4e-13: 72.3: 12.64