HitPredict

Interactor 1: UBI4P (P0CG63)
Polyubiquitin [Cleaved into: Ubiquitin]
Gene: UBI4

Interactor 2: UBA3 (Q99344)
NEDD8-activating enzyme E1 catalytic subunit (EC 6.2.1.64) (RUB1-activating enzyme E1) (Ubiquitin-activating enzyme E1 3) (Ubiquitin-like protein-activating enzyme)
Gene: UBA3

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	38803224
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	ThiF~ubiquitin
Common GO terms	GO:0005634 - nucleus
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 381 Sc			1 299
+	Rn
		1144252 UBC_RAT (1-333): 8.71e-131: 395: 93.99		UBA3_RAT (3-299): 8.89e-113: 335: 41.61
+	Sc
		477271 UBI4P_YEAST (1-381): 4.37e-161: 458: 100.00		UBA4_YEAST (2-161): 4.2e-48: 167: 29.01
+	Sc
		477133 UBI4P_YEAST (1-381): 4.37e-161: 458: 100.00		UBA1_YEAST (3-144): 8.06e-21: 94.4: 23.78
+	Mm
		476770 UBC_MOUSE (1-333): 9.24e-132: 396: 93.99		UBA1_MOUSE (3-143): 1.1e-24: 105: 24.82
+	Rn
		1137285 UBC_RAT (1-333): 8.71e-131: 395: 93.99		UBA1_RAT (3-143): 1.01e-23: 103: 24.82
+	Mm
		476902 UBC_MOUSE (1-333): 9.24e-132: 396: 93.99		UBA6_MOUSE (2-143): 3.99e-18: 86.7: 20.00
+	At
		955613 UBQ3_ARATH (77-381): 2.59e-125: 365: 97.05		UBE11_ARATH (3-227): 5.1e-20: 92.1: 20.89
+	Hs
		476506 UBC_HUMAN (1-153): 1.84e-50: 181: 95.43		SAE2_HUMAN (4-263): 4.21e-73: 238: 31.56
+	Hs
		171508 UBD_HUMAN (231-380): 1.48e-30: 116: 30.77		SAE2_HUMAN (4-263): 4.21e-73: 238: 31.56
+	Hs
		171506 UBD_HUMAN (231-380): 1.48e-30: 116: 30.77		SAE1_HUMAN (3-276): 3.17e-73: 230: 15.11
+	Hs
		475337 UBC_HUMAN (1-153): 1.84e-50: 181: 95.43		UBA1_HUMAN (3-143): 7.98e-24: 103: 24.82
+	Hs
		48090 UBC_HUMAN (1-153): 1.84e-50: 181: 95.43		UBA6_HUMAN (2-143): 2.65e-20: 93.2: 19.31
+	Sc
		408274 RS31_YEAST (305-380): 1.88e-41: 144: 100.00		UBA1_YEAST (3-144): 8.06e-21: 94.4: 23.78
+	Hs
		171474 UBD_HUMAN (231-380): 1.48e-30: 116: 30.77		UBA1_HUMAN (3-143): 7.98e-24: 103: 24.82
+	Hs
		397822 ISG15_HUMAN (3-152): 9.45e-31: 117: 32.68		UBA7_HUMAN (3-141): 1.22e-20: 94: 23.74
+	Hs
		48082 UBD_HUMAN (231-380): 1.48e-30: 116: 30.77		UBA6_HUMAN (2-143): 2.65e-20: 93.2: 19.31
+	Hs
		607051 RS27A_HUMAN (77-153): 8.44e-20: 87: 94.81		UBA1_HUMAN (3-143): 7.98e-24: 103: 24.82