HitPredict

Interactor 1: HMGB1 (P09429)
High mobility group protein B1 (High mobility group protein 1) (HMG-1)
Gene: HMGB1

Interactor 2: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34349018
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0043005 - neuron projection GO:0043410 - positive regulation of MAPK cascade
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 215 Hs			1 191
+	Hs
		481218 HMGB1_HUMAN (1-174): 9.5e-45: 150: 100.00		RAC1_HUMAN (1-191): 1.15e-81: 242: 70.31
+	Hs
		73878 HGB1A_HUMAN (1-174): 4.64e-42: 142: 94.83		RAC1_HUMAN (1-191): 1.15e-81: 242: 70.31
+	Hs
		186641 HMGB3_HUMAN (13-181): 1.46e-41: 141: 71.60		RAC1_HUMAN (1-191): 1.15e-81: 242: 70.31
+	Hs
		872177 SOX2_HUMAN (3-94): 7.23e-25: 100: 23.91		RAC1_HUMAN (1-191): 1.15e-81: 242: 70.31
+	Hs
		872144 SOX2_HUMAN (3-94): 7.23e-25: 100: 23.91		RHOA_HUMAN (5-191): 2.51e-78: 233: 53.48
+	Hs
		604625 UBF1_HUMAN (10-158): 4.17e-09: 57.8: 23.60		RAC3_HUMAN (1-177): 7.58e-76: 227: 72.32