HitPredict

Interactor 1: HMGB1 (P09429)
High mobility group protein B1 (High mobility group protein 1) (HMG-1)
Gene: HMGB1

Interactor 2: FYCO1 (Q9BQS8)
FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7)
Gene: FYCO1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	34535262
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 215 Hs			1 1478
+	Hs
		157285 SSRP1_HUMAN (53-164): 1.6e-28: 114: 37.50		CTRO_HUMAN (195-970): 2.93e-38: 159: 15.06
+	Hs
		659173 SP100_HUMAN (25-178): 7.58e-34: 129: 87.66		MYH9_HUMAN (574-1367): 8.52e-33: 141: 12.76
+	Hs
		157082 SOX2_HUMAN (3-94): 7.23e-25: 100: 23.91		CTRO_HUMAN (195-970): 2.93e-38: 159: 15.06
+	Hs
		1065210 SSRP1_HUMAN (53-164): 1.6e-28: 114: 37.50		EEA1_HUMAN (1-727): 2.37e-29: 129: 12.52
+	Hs
		156930 UBF1_HUMAN (10-158): 4.17e-09: 57.8: 23.60		CTRO_HUMAN (195-970): 2.93e-38: 159: 15.06
+	Hs
		157245 TFAM_HUMAN (95-186): 2.96e-09: 57.1: 17.39		CTRO_HUMAN (195-970): 2.93e-38: 159: 15.06
+	Hs
		773125 SOX2_HUMAN (3-94): 7.23e-25: 100: 23.91		MYH10_HUMAN (5-484): 1.16e-17: 91.8: 9.50
+	Hs
		587588 SOX2_HUMAN (3-94): 7.23e-25: 100: 23.91		DESP_HUMAN (232-1121): 6.85e-14: 79.7: 22.05
+	Hs
		872350 SOX2_HUMAN (3-94): 7.23e-25: 100: 23.91		PLEC_HUMAN (385-1169): 2.59e-09: 64.7: 22.38
+	Mm
		98057 SOX17_MOUSE (4-90): 4.12e-22: 94.8: 18.39		DESP_MOUSE (224-829): 7.5e-10: 66.2: 19.06
+	Hs
		587777 CIC_HUMAN (3-96): 6.88e-12: 65.9: 22.34		DESP_HUMAN (232-1121): 6.85e-14: 79.7: 22.05
+	Ce
		1067135 HMGBH_CAEEL (2-82): 1.86e-10: 60.5: 32.10		Q20641_CAEEL (295-1143): 8.8e-10: 65.9: 19.54