HitPredict

Interactor 1: TPM1 (P09493)
Tropomyosin alpha-1 chain (Alpha-tropomyosin) (Tropomyosin-1)
Gene: TPM1

Interactor 2: TMOD1 (P28289)
Tropomodulin-1 (Erythrocyte tropomodulin) (E-Tmod)
Gene: TMOD1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Tropomodulin~Tropomyosin
Common GO terms	GO:0003779 - actin binding GO:0005829 - cytosol GO:0005856 - cytoskeleton GO:0005884 - actin filament GO:0007015 - actin filament organization and 1 others more... GO:0030017 - sarcomere
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 284 Hs			1 359
+	Hs
		447682 TPM3_HUMAN (1-284): 1.02e-43: 152: 91.20		TMOD1_HUMAN (1-359): 1.53e-167: 473: 100.00
+	Hs
		701970 TPM4_HUMAN (42-284): 3.78e-33: 123: 68.72		TMOD1_HUMAN (1-359): 1.53e-167: 473: 100.00
+	Dm
		883979 TPM4_DROME (1-281): 7.3e-35: 133: 55.52		Q9VA56_DROME (3-346): 1.28e-123: 363: 36.86
+	Hs
		482966 TPM1_HUMAN (1-284): 2.36e-44: 153: 100.00		NOD2_HUMAN (171-333): 6.74e-12: 69: 18.41
+	Hs
		447863 TPM3_HUMAN (1-284): 1.02e-43: 152: 91.20		NOD2_HUMAN (171-333): 6.74e-12: 69: 18.41
+	Hs
		995481 TPM4_HUMAN (42-284): 3.78e-33: 123: 68.72		NOD2_HUMAN (171-333): 6.74e-12: 69: 18.41