HitPredict

Interactor 1: TPM1 (P09493)
Tropomyosin alpha-1 chain (Alpha-tropomyosin) (Tropomyosin-1)
Gene: TPM1

Interactor 2: MYO19 (Q96H55)
Unconventional myosin-XIX (Myosin head domain-containing protein 1)
Gene: MYO19

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Myosin_head~Tropomyosin
Common GO terms	GO:0003779 - actin binding GO:0005829 - cytosol GO:0007015 - actin filament organization GO:0015629 - actin cytoskeleton GO:0051015 - actin filament binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 284 Hs			1 970
+	Hs
		447835 TPM3_HUMAN (1-284): 1.02e-43: 152: 91.20		MYO19_HUMAN (1-970): 0: 1069: 100.00
+	Hs
		464198 TPM2_HUMAN (1-284): 1.4e-38: 138: 85.56		MYO19_HUMAN (1-970): 0: 1069: 100.00
+	Hs
		116469 H7BYY1_HUMAN (41-284): 8.18e-35: 127: 70.49		MYO19_HUMAN (1-970): 0: 1069: 100.00
+	Hs
		995462 TPM4_HUMAN (42-284): 3.78e-33: 123: 68.72		MYO19_HUMAN (1-970): 0: 1069: 100.00
+	Dm
		447919 TPM1_DROME (1-281): 3.08e-56: 186: 44.78		Q59E59_DROME (9-898): 0: 986: 28.21
+	Hs
		482842 TPM1_HUMAN (1-284): 2.36e-44: 153: 100.00		MYH9_HUMAN (9-907): 0: 997: 28.63
+	Hs
		447692 TPM3_HUMAN (1-284): 1.02e-43: 152: 91.20		MYH9_HUMAN (9-907): 0: 997: 28.63
+	Hs
		464124 TPM2_HUMAN (1-284): 1.4e-38: 138: 85.56		MYH9_HUMAN (9-907): 0: 997: 28.63
+	Hs
		116462 H7BYY1_HUMAN (41-284): 8.18e-35: 127: 70.49		MYH9_HUMAN (9-907): 0: 997: 28.63
+	Hs
		772732 TPM4_HUMAN (42-284): 3.78e-33: 123: 68.72		MYH9_HUMAN (9-907): 0: 997: 28.63