Interactor 1: CALM3 (P0DP25)
Calmodulin-3
Gene: CALM3
Interactor 2: CAC1C (Q13936)
Voltage-dependent L-type calcium channel subunit alpha-1C (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Voltage-gated calcium channel subunit alpha Cav1.2)
Gene: CACNA1C
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.53 | 1.00 | 0.730 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 20953164 |
| Identification Methods | x-ray crystallography, isothermal titration calorimetry, pull down, cosedimentation in solution |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Ca_chan_IQ~EF-hand_7, EF-hand_7~Ion_trans |
| Common GO terms | GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0010881 - regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion |
| Homologous interactions | 3 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
