Protein: EPHA6
Ephrin type-A receptor 6 (EC 2.7.10.1) (EPH homology kinase 2) (EHK-2) (EPH-like kinase 12) (EK12)

Gene: EPHA6
Organism: Homo sapiens
Interactions: 41
UniProt ID: Q9UF33

Gene Ontology (top 5):
GO:0005005 - transmembrane-ephrin receptor activity
GO:0005524 - ATP binding
GO:0005886 - plasma membrane
GO:0007411 - axon guidance
GO:0030425 - dendrite

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

710546

EPHA2
Ephrin type-A receptor 2

2

19

High-throughput

0.820

High

914367

EFNA4
Ephrin-A4

2

20

High-throughput

0.789

High

914560

EFNA5
Ephrin-A5

1

20

High-throughput

0.691

High

932006

EPHB4
Ephrin type-B receptor 4

1

18

High-throughput

0.691

High

710910

EPHB2
Ephrin type-B receptor 2

1

18

High-throughput

0.646

High

416655

REL1
Prorelaxin H1 [Cleaved into: Relaxin B chain; Relaxin A chain]

1

1

High-throughput

0.618

High

468876

HS90B
Heat shock protein HSP 90-beta

1

20

High-throughput

0.618

High

953738

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.618

High

1048397

ACVR1
Activin receptor type-1

1

15

Small-scale

0.618

High

296588

STAM2
Signal transducing adapter molecule 2

1

20

High-throughput

0.578

High

402477

PROC
Vitamin K-dependent protein C

2

16

High-throughput

0.574

High

67716

RHG32
Rho GTPase-activating protein 32

1

20

High-throughput

0.553

High

1158586

CDC37
Hsp90 co-chaperone Cdc37

1

20

High-throughput

0.553

High

1277797

MYH14
Myosin-14

1

7

High-throughput

0.536

High

318412

MYO1D
Unconventional myosin-Id

1

17

High-throughput

0.500

High

169781

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

20

High-throughput

0.489

High

1150960

TRIPB
Thyroid receptor-interacting protein 11

1

20

High-throughput

0.489

High

444009

ATPB
ATP synthase F(1) complex subunit beta, mitochondrial

1

4

High-throughput

0.479

High

717359

PEBP1
Phosphatidylethanolamine-binding protein 1

1

3

High-throughput

0.479

High

957858

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

6

High-throughput

0.479

High

1404917

PARK7
Parkinson disease protein 7

1

2

High-throughput

0.479

High

1439720

JPH1
Junctophilin-1

1

9

High-throughput

0.479

High

1459072

STML2
Stomatin-like protein 2, mitochondrial

1

7

High-throughput

0.479

High

663457

RIR1
Ribonucleoside-diphosphate reductase large subunit

1

0

High-throughput

0.458

High

1148483

SAFB1
Scaffold attachment factor B1

1

17

High-throughput

0.457

High

255264

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

13

High-throughput

0.445

High

1119347

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

13

High-throughput

0.445

High

389767

FETUA
Alpha-2-HS-glycoprotein

1

3

High-throughput

0.437

High

488564

UCHL1
Ubiquitin carboxyl-terminal hydrolase isozyme L1

1

4

High-throughput

0.437

High

717178

ECHM
Enoyl-CoA hydratase, mitochondrial

1

11

High-throughput

0.437

High

894604

GDIB
Rab GDP dissociation inhibitor beta

1

1

High-throughput

0.437

High

1113011

CUL2
Cullin-2

1

4

High-throughput

0.437

High

1148958

SC23A
Protein transport protein Sec23A

1

20

High-throughput

0.437

High

1149040

SC23B
Protein transport protein Sec23B

1

20

High-throughput

0.437

High

1155868

EZH2
Histone-lysine N-methyltransferase EZH2

1

9

High-throughput

0.437

High

1203916

NOM1
Nucleolar MIF4G domain-containing protein 1

1

2

High-throughput

0.437

High

1409869

RBM4B
RNA-binding protein 4B

1

11

High-throughput

0.437

High

1403682

GPHA2
Glycoprotein hormone alpha-2

3

0

High-throughput

0.347

High

1030820

DEF5
Defensin alpha 5

2

0

High-throughput

0.328

High

276798

TBCA
Tubulin-specific chaperone A

1

0

High-throughput

0.249

Low

1143988

IPYR
Inorganic pyrophosphatase

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025