HitPredict

Interactor 1: PGFRB (P09619)
Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)
Gene: PDGFRB

Interactor 2: RN149 (Q8NC42)
E3 ubiquitin-protein ligase RNF149 (EC 2.3.2.27) (DNA polymerase-transactivated protein 2) (RING finger protein 149) (RING-type E3 ubiquitin transferase RNF149)
Gene: RNF149

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005794 - Golgi apparatus GO:0016020 - membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1106 Hs			1 400
+	Hs
		541594 FGFR1_HUMAN (218-720): 1.28e-70: 254: 20.44		RN149_HUMAN (1-400): 1.38e-131: 385: 100.00
+	Hs
		1101757 PTK7_HUMAN (28-521): 8.14e-45: 178: 12.70		RN149_HUMAN (1-400): 1.38e-131: 385: 100.00
+	Hs
		541574 FGFR1_HUMAN (218-720): 1.28e-70: 254: 20.44		GOLI_HUMAN (30-374): 2.51e-87: 272: 40.52
+	Hs
		641211 FGFR2_HUMAN (38-328): 3.54e-22: 105: 13.31		RN149_HUMAN (1-400): 1.38e-131: 385: 100.00
+	Hs
		1101759 PTK7_HUMAN (28-521): 8.14e-45: 178: 12.70		RN128_HUMAN (7-387): 1.02e-93: 289: 37.98
+	Hs
		650276 FGFR3_HUMAN (203-413): 8.48e-15: 81.4: 19.18		GOLI_HUMAN (30-374): 2.51e-87: 272: 40.52
+	Hs
		648575 FGFR4_HUMAN (200-413): 5.3e-14: 78.7: 17.73		GOLI_HUMAN (30-374): 2.51e-87: 272: 40.52