Protein: PTK7
Inactive tyrosine-protein kinase 7 (Colon carcinoma kinase 4) (CCK-4) (Protein-tyrosine kinase 7) (Pseudo tyrosine kinase receptor 7) (Tyrosine-protein kinase-like 7)

Gene: PTK7
Organism: Homo sapiens
Interactions: 147
UniProt ID: Q13308

Gene Ontology (top 5):
GO:0001736 - establishment of planar polarity
GO:0001822 - kidney development
GO:0001843 - neural tube closure
GO:0003281 - ventricular septum development
GO:0003401 - axis elongation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

375481

RASK
GTPase KRas

3

17

High-throughput

0.827

High

596976

TSHR
Thyrotropin receptor

2

12

High-throughput

0.789

High

761217

RYK
Tyrosine-protein kinase RYK

2

18

Small-scale

0.789

High

1101730

PTPRO
Receptor-type tyrosine-protein phosphatase O

2

20

High-throughput

0.789

High

1101739

BTNL8
Butyrophilin-like protein 8

2

3

High-throughput

0.789

High

410811

ERBB2
Receptor tyrosine-protein kinase erbB-2

2

20

Small-scale

0.767

High

1101793

ALK
ALK tyrosine kinase receptor

2

20

Small-scale

0.754

High

711119

PTN6
Tyrosine-protein phosphatase non-receptor type 6

1

20

High-throughput

0.698

High

767050

PTN7
Tyrosine-protein phosphatase non-receptor type 7

1

20

High-throughput

0.698

High

1050786

PTN12
Tyrosine-protein phosphatase non-receptor type 12

1

20

High-throughput

0.698

High

1053657

PTN11
Tyrosine-protein phosphatase non-receptor type 11

1

20

High-throughput

0.698

High

1101727

PTPRR
Receptor-type tyrosine-protein phosphatase R

1

20

High-throughput

0.698

High

472055

MET
Hepatocyte growth factor receptor

1

20

High-throughput

0.691

High

731840

CEAM8
Cell adhesion molecule CEACAM8

1

20

High-throughput

0.691

High

1101789

BTNL2
Butyrophilin-like protein 2

1

20

High-throughput

0.691

High

1101746

CLNK
Cytokine-dependent hematopoietic cell linker

2

20

High-throughput

0.686

High

439722

INSR
Insulin receptor

1

20

High-throughput

0.646

High

465508

IGF1R
Insulin-like growth factor 1 receptor

1

20

High-throughput

0.646

High

648502

FGFR4
Fibroblast growth factor receptor 4

1

16

High-throughput

0.646

High

777679

VGFR3
Vascular endothelial growth factor receptor 3

1

20

High-throughput

0.646

High

1055045

TYRO3
Tyrosine-protein kinase receptor TYRO3

1

19

High-throughput

0.646

High

1101729

NTRK3
NT-3 growth factor receptor

1

19

High-throughput

0.646

High

1101747

TM11B
Transmembrane protease serine 11B

2

2

High-throughput

0.621

High

164327

NRP1
Neuropilin-1

1

9

High-throughput

0.618

High

373908

RASN
GTPase NRas

1

18

High-throughput

0.618

High

374565

RASH
GTPase HRas

1

16

High-throughput

0.618

High

411864

NTRK1
High affinity nerve growth factor receptor

1

17

High-throughput

0.618

High

463499

LYN
Tyrosine-protein kinase Lyn

1

20

High-throughput

0.618

High

463952

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

17

High-throughput

0.618

High

484125

PGFRB
Platelet-derived growth factor receptor beta

1

20

High-throughput

0.618

High

710220

EPHA2
Ephrin type-A receptor 2

1

20

High-throughput

0.618

High

1101742

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.618

High

1101743

RHOU
Rho-related GTP-binding protein RhoU

1

9

High-throughput

0.618

High

1101777

RHOJ
Rho-related GTP-binding protein RhoJ

1

5

High-throughput

0.618

High

1101778

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.618

High

1101795

AT1B4
Protein ATP1B4

2

4

High-throughput

0.611

High

950468

KR108
Keratin-associated protein 10-8

2

11

High-throughput

0.606

High

1101749

KRA13
Keratin-associated protein 1-3

2

11

High-throughput

0.606

High

480781

LEG1
Galectin-1

2

3

High-throughput

0.601

High

1101794

CLC4A
C-type lectin domain family 4 member A

2

7

High-throughput

0.601

High

540435

LAMP1
Lysosome-associated membrane glycoprotein 1

2

2

High-throughput

0.588

High

1101772

ACE2
Angiotensin-converting enzyme 2

2

2

Small-scale

0.584

High

717298

PEBP1
Phosphatidylethanolamine-binding protein 1

2

2

High-throughput

0.571

High

1101724

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

2

9

High-throughput

0.571

High

1101734

MTUS2
Microtubule-associated tumor suppressor candidate 2

2

20

High-throughput

0.553

High

1101770

MDFI
MyoD family inhibitor

2

2

High-throughput

0.553

High

1101731

CEA21
Cell adhesion molecule CEACAM21

1

20

High-throughput

0.553

High

1101766

LRC59
Leucine-rich repeat-containing protein 59

1

20

High-throughput

0.553

High

1101784

S17A5
Sialin

1

0

High-throughput

0.546

High

290924

PPM1B
Protein phosphatase 1B

1

5

High-throughput

0.541

High

593839

PP2BB
Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform

1

4

High-throughput

0.541

High

776952

PPM1A
Protein phosphatase 1A

1

4

High-throughput

0.541

High

884823

PPM1F
Protein phosphatase 1F

1

9

High-throughput

0.541

High

939920

TPTE
Putative tyrosine-protein phosphatase TPTE

1

9

High-throughput

0.541

High

951654

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

9

High-throughput

0.541

High

1062363

PP2BA
Protein phosphatase 3 catalytic subunit alpha

1

4

High-throughput

0.541

High

1101723

MTMR1
Phosphatidylinositol-3-phosphate phosphatase MTMR1

1

14

High-throughput

0.541

High

1101740

TPTE2
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2

1

10

High-throughput

0.541

High

1101761

STYX
Serine/threonine/tyrosine-interacting protein

1

10

High-throughput

0.541

High

1101768

MTMR9
Myotubularin-related protein 9

1

14

High-throughput

0.541

High

1101774

ILKAP
Integrin-linked kinase-associated serine/threonine phosphatase 2C

1

10

High-throughput

0.541

High

1101775

DUS15
Dual specificity protein phosphatase 15

1

12

High-throughput

0.541

High

1101786

MTMRA
Myotubularin-related protein 10

1

14

High-throughput

0.541

High

1101796

CC14A
Dual specificity protein phosphatase CDC14A

1

10

High-throughput

0.541

High

1101797

MTMR6
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR6

1

14

High-throughput

0.541

High

1101799

DUS10
Dual specificity protein phosphatase 10

1

12

High-throughput

0.541

High

1101764

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

9

High-throughput

0.536

High

764719

CTNB1
Catenin beta-1

1

16

Small-scale

0.529

High

188878

TMPS2
Transmembrane protease serine 2

1

2

High-throughput

0.515

High

580625

AMPN
Aminopeptidase N

1

4

High-throughput

0.515

High

620341

NUCL
Nucleolin

1

11

High-throughput

0.515

High

692951

DPP4
Dipeptidyl peptidase 4

1

3

High-throughput

0.515

High

1101785

TMPS4
Transmembrane protease serine 4

1

2

High-throughput

0.515

High

1101792

CLC4E
C-type lectin domain family 4 member E

1

7

High-throughput

0.515

High

946550

EVA1C
Protein eva-1 homolog C

1

5

High-throughput

0.514

High

1101726

MFS10
Major facilitator superfamily domain-containing protein 10

1

7

High-throughput

0.514

High

1101751

S22A9
Organic anion transporter 7

1

2

High-throughput

0.514

High

1101752

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

158566

CTDS2
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2

1

5

High-throughput

0.494

High

326700

DUS14
Dual specificity protein phosphatase 14

1

12

High-throughput

0.494

High

1101736

DUS29
Dual specificity phosphatase 29

1

11

High-throughput

0.494

High

1101754

PPM1K
Protein phosphatase Mn(2+)-dependent 1K

1

7

High-throughput

0.494

High

1101758

DUS18
Dual specificity protein phosphatase 18

1

10

High-throughput

0.494

High

1101760

DUS19
Dual specificity protein phosphatase 19

1

10

High-throughput

0.494

High

1101771

DUS26
Dual specificity protein phosphatase 26

1

10

High-throughput

0.494

High

1101779

DUS21
Dual specificity protein phosphatase 21

1

12

High-throughput

0.494

High

342550

LY86
Lymphocyte antigen 86

1

2

High-throughput

0.489

High

698625

CALX
Calnexin

1

15

High-throughput

0.489

High

1101328

SG2A2
Mammaglobin-A

1

2

High-throughput

0.489

High

685844

KRA59
Keratin-associated protein 5-9

1

13

High-throughput

0.481

High

1059630

KRA11
Keratin-associated protein 1-1

1

11

High-throughput

0.481

High

218143

TGON2
Trans-Golgi network integral membrane protein 2

1

11

High-throughput

0.479

High

293649

CD123
Translation initiation factor eIF2 assembly protein

1

1

High-throughput

0.479

High

295325

EIF3J
Eukaryotic translation initiation factor 3 subunit J

1

1

High-throughput

0.479

High

951133

SC61B
Protein transport protein Sec61 subunit beta

1

2

High-throughput

0.479

High

1101722

SMAD4
Mothers against decapentaplegic homolog 4

1

1

High-throughput

0.479

High

1101725

FZD2
Frizzled-2

1

6

High-throughput

0.479

High

1101759

RN128
E3 ubiquitin-protein ligase RNF128

1

9

High-throughput

0.479

High

1101776

DNJC5
DnaJ homolog subfamily C member 5

1

18

High-throughput

0.479

High

1101787

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.479

High

1101798

TRAF6
TNF receptor-associated factor 6

1

12

Small-scale

0.479

High

517001

NT2NC
Notch homolog 2 N-terminal-like protein C

1

11

High-throughput

0.470

High

1101738

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

255001

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

7

High-throughput

0.445

High

256028

S19A2
Thiamine transporter 1

1

2

High-throughput

0.445

High

388403

B3AT
Band 3 anion transport protein

1

9

High-throughput

0.445

High

722451

CTR1
High affinity cationic amino acid transporter 1

1

6

High-throughput

0.445

High

834963

S19A1
Reduced folate transporter

1

2

High-throughput

0.445

High

870229

S6A12
Sodium- and chloride-dependent betaine transporter

1

7

High-throughput

0.445

High

870357

S6A11
Sodium- and chloride-dependent GABA transporter 3

1

7

High-throughput

0.445

High

880134

PTH2R
Parathyroid hormone 2 receptor

1

6

High-throughput

0.445

High

1097247

S13A2
Solute carrier family 13 member 2

1

1

High-throughput

0.445

High

1101728

AAAT
Neutral amino acid transporter B(0)

1

7

High-throughput

0.445

High

1101732

S22A6
Solute carrier family 22 member 6

1

2

High-throughput

0.445

High

1101733

S39AC
Zinc transporter ZIP12

1

10

High-throughput

0.445

High

1101737

GTR7
Solute carrier family 2, facilitated glucose transporter member 7

1

3

High-throughput

0.445

High

1101741

S39A5
Zinc transporter ZIP5

1

10

High-throughput

0.445

High

1101744

NIPA1
Magnesium transporter NIPA1

1

1

High-throughput

0.445

High

1101755

CTL3
Choline transporter-like protein 3

1

1

High-throughput

0.445

High

1101762

CTL1
Choline transporter-like protein 1

1

1

High-throughput

0.445

High

1101763

CTR3
Cationic amino acid transporter 3

1

4

High-throughput

0.445

High

1101773

S13A1
Solute carrier family 13 member 1

1

1

High-throughput

0.445

High

1101781

ANKH
Mineralization regulator ANKH

1

1

High-throughput

0.445

High

1101783

SO1B3
Solute carrier organic anion transporter family member 1B3

1

3

High-throughput

0.445

High

1101788

SO3A1
Solute carrier organic anion transporter family member 3A1

1

3

High-throughput

0.445

High

1101790

FBX2
F-box only protein 2

1

11

High-throughput

0.445

High

1101791

S39AA
Zinc transporter ZIP10

1

10

High-throughput

0.445

High

515

NBPFJ
NBPF family member NBPF19

1

8

High-throughput

0.439

High

1101745

NT2NA
Notch homolog 2 N-terminal-like protein A

1

10

High-throughput

0.439

High

1004518

RNF4
E3 ubiquitin-protein ligase RNF4

1

4

High-throughput

0.437

High

1101735

MARH8
E3 ubiquitin-protein ligase MARCHF8

1

2

High-throughput

0.437

High

1101750

PLD3
5'-3' exonuclease PLD3

1

4

High-throughput

0.437

High

1101757

RN149
E3 ubiquitin-protein ligase RNF149

1

9

High-throughput

0.437

High

1101767

PLD4
5'-3' exonuclease PLD4

1

4

High-throughput

0.437

High

1101769

SDF2
Stromal cell-derived factor 2

1

9

High-throughput

0.437

High

749325

TNFL8
Tumor necrosis factor ligand superfamily member 8

1

0

High-throughput

0.426

High

1101780

S28A3
Solute carrier family 28 member 3

1

0

High-throughput

0.426

High

1101782

S40A1
Ferroportin

1

0

High-throughput

0.426

High

1101756

SIGL1
SIGLEC family-like protein 1

1

1

High-throughput

0.407

High

407851

SEMG1
Semenogelin-1

1

0

High-throughput

0.269

Low

925915

TCP4
Activated RNA polymerase II transcriptional coactivator p15

1

0

High-throughput

0.269

Low

70195

CRTP1
Cysteine-rich tail protein 1

1

0

High-throughput

0.251

Low

1101748

TMM17
Transmembrane protein 17

1

0

High-throughput

0.249

Low

1101765

CK052
Uncharacterized protein C11orf52

1

0

High-throughput

0.249

Low

653293

HEMH
Ferrochelatase, mitochondrial

1

0

High-throughput

0.232

Low

1007376

S35A2
UDP-galactose translocator

1

0

High-throughput

0.232

Low

1101753

S35F3
Solute carrier family 35 member F3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025