HitPredict

Interactor 1: NT2NC (P0DPK4)
Notch homolog 2 N-terminal-like protein C
Gene: NOTCH2NLC

Interactor 2: NECT2 (Q92692)
Nectin-2 (Herpes virus entry mediator B) (Herpesvirus entry mediator B) (HveB) (Nectin cell adhesion molecule 2) (Poliovirus receptor-related protein 2) (CD antigen CD112)
Gene: NECTIN2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.80	0.594

Property	Details
Experiments	unassigned1304
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	EGF~V-set
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 293 Hs			1 538
+	Hs
		484720 NT2NC_HUMAN (1-293): 1.76e-48: 164: 100.00		NECT3_HUMAN (30-389): 3.83e-72: 241: 25.00
+	Hs
		484560 NT2NC_HUMAN (1-293): 1.76e-48: 164: 100.00		PVR_HUMAN (25-441): 3.32e-61: 209: 42.72
+	Hs
		1189382 NT2NA_HUMAN (22-229): 8.21e-15: 73.9: 30.37		NECT2_HUMAN (1-538): 1.67e-89: 287: 100.00
+	Hs
		484728 NT2NC_HUMAN (1-293): 1.76e-48: 164: 100.00		NTRI_HUMAN (20-360): 4.8e-54: 187: 15.58
+	Hs
		1189463 NT2NA_HUMAN (22-229): 8.21e-15: 73.9: 30.37		NECT3_HUMAN (30-389): 3.83e-72: 241: 25.00
+	Hs
		484602 NT2NC_HUMAN (1-293): 1.76e-48: 164: 100.00		PTK7_HUMAN (4-527): 3.59e-35: 142: 14.13
+	Hs
		545132 NT2NA_HUMAN (22-229): 8.21e-15: 73.9: 30.37		PVR_HUMAN (25-441): 3.32e-61: 209: 42.72
+	Hs
		1189476 NT2NA_HUMAN (22-229): 8.21e-15: 73.9: 30.37		NTRI_HUMAN (20-360): 4.8e-54: 187: 15.58
+	Ce
		103935 SLIT1_CAEEL (202-281): 5.31e-12: 68.1: 25.93		SAX3_CAEEL (33-444): 1.01e-47: 180: 13.54
+	Hs
		1031145 NT2NA_HUMAN (22-229): 8.21e-15: 73.9: 30.37		PTK7_HUMAN (4-527): 3.59e-35: 142: 14.13
+	Dm
		621596 SLIT_DROME (13-162): 2.9e-24: 104: 23.90		Q9VQ08_DROME (348-538): 5.69e-20: 96.3: 10.26
+	Dm
		621592 SLIT_DROME (13-162): 2.9e-24: 104: 23.90		Q9GPP7_DROME (348-538): 7.31e-20: 95.9: 10.26
+	Dm
		219803 SLIT_DROME (13-162): 2.9e-24: 104: 23.90		O44924_DROME (347-538): 1.1e-16: 85.9: 9.27
+	Dm
		621597 SLIT_DROME (13-162): 2.9e-24: 104: 23.90		Q9W213_DROME (347-538): 1.05e-16: 85.9: 9.27
+	Dm
		621591 SLIT_DROME (13-162): 2.9e-24: 104: 23.90		Q9GPP6_DROME (24-365): 1.04e-15: 82.9: 9.24
+	Dm
		621595 SLIT_DROME (13-162): 2.9e-24: 104: 23.90		Q9VPZ7_DROME (24-365): 9.53e-16: 82.9: 9.24
+	Dm
		621590 SLIT_DROME (13-162): 2.9e-24: 104: 23.90		Q5U176_DROME (382-538): 4.47e-13: 74.4: 10.06
+	Hs
		296682 SLIT2_HUMAN (43-170): 1.65e-10: 63.5: 24.62		ROBO1_HUMAN (333-538): 1.79e-18: 91.7: 8.92
+	Dr
		1265014 Q9DE36_DANRE (39-166): 3.01e-10: 62.8: 25.39		Q90Z70_DANRE (448-538): 1.53e-10: 66.3: 14.00
+	Dr
		65452 Q9DE36_DANRE (39-166): 3.01e-10: 62.8: 25.39		A8DZ85_DANRE (450-538): 1.26e-09: 63.2: 15.31