HitPredict

Interactor 1: IF4A (P10081)
ATP-dependent RNA helicase eIF4A (EC 3.6.4.13) (Eukaryotic initiation factor 4A) (eIF-4A) (Stimulator factor I 37 kDa component) (Translation initiation factor 1/2) (p37)
Gene: TIF1

Interactor 2: IF4A (P10081)
ATP-dependent RNA helicase eIF4A (EC 3.6.4.13) (Eukaryotic initiation factor 4A) (eIF-4A) (Stimulator factor I 37 kDa component) (Translation initiation factor 1/2) (p37)
Gene: TIF1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.830

The method score is based on:

Property Details
Experiments 16554755, 37968396, 16429126
Identification Methods affinity chromatography technology, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains DEAD~DEAD, DEAD~Helicase_C, Helicase_C~Helicase_C
Common GO terms GO:0002183 - cytoplasmic translational initiation
GO:0003723 - RNA binding
GO:0003724 - RNA helicase activity
GO:0003743 - translation initiation factor activity
GO:0005524 - ATP binding
and 10 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 395
Sc

1 395
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Hs
+ Sc
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Hs
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024