Interactor 1: CCL3 (P10147)
C-C motif chemokine 3 (G0/G1 switch regulatory protein 19-1) (Macrophage inflammatory protein 1-alpha) (MIP-1-alpha) (PAT 464.1) (SIS-beta) (Small-inducible cytokine A3) (Tonsillar lymphocyte LD78 alpha protein) [Cleaved into: MIP-1-alpha(4-69) (LD78-alpha(4-69))]
Gene: CCL3
Interactor 2: IDE (P14735)
Insulin-degrading enzyme (EC 3.4.24.56) (Abeta-degrading protease) (Insulin protease) (Insulinase) (Insulysin)
Gene: IDE
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.57 | 0.60 | 0.586 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 20959807 |
| Identification Methods | x-ray crystallography, protease assay, competition binding |
| Interaction Type | direct interaction, cleavage reaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005615 - extracellular space GO:0005737 - cytoplasm GO:0005829 - cytosol |
| Homologous interactions | 4 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
