HitPredict

Interactor 1: CCL2 (P10148)
C-C motif chemokine 2 (Monocyte chemoattractant protein 1) (Monocyte chemotactic protein 1) (MCP-1) (Platelet-derived growth factor-inducible protein JE) (Small-inducible cytokine A2)
Gene: CCL2

Interactor 2: NFAT5 (Q9WV30)
Nuclear factor of activated T-cells 5 (NF-AT5) (Rel domain-containing transcription factor NFAT5) (T-cell transcription factor NFAT5)
Gene: NFAT5

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	20685965
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0010628 - positive regulation of gene expression
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 148 Mm			1 1534
+	Mm
		486356 CCL2_MOUSE (1-127): 1.23e-46: 149: 100.00		NFKB1_MOUSE (271-779): 1.62e-91: 322: 15.17
+	Hs
		587597 CCL14_HUMAN (1-93): 5.56e-34: 115: 30.85		NFKB1_HUMAN (271-787): 3.02e-91: 321: 14.56
+	Hs
		528199 CCL2_HUMAN (1-98): 2.89e-33: 114: 52.04		NFKB1_HUMAN (271-787): 3.02e-91: 321: 14.56
+	Hs
		587476 CCL11_HUMAN (1-99): 1.36e-32: 112: 47.48		NFKB1_HUMAN (271-787): 3.02e-91: 321: 14.56
+	Mm
		638438 CCL5_MOUSE (1-93): 9.06e-32: 110: 35.48		NFKB1_MOUSE (271-779): 1.62e-91: 322: 15.17
+	Hs
		587522 CCL20_HUMAN (9-97): 1.85e-24: 92.1: 22.22		NFKB1_HUMAN (271-787): 3.02e-91: 321: 14.56
+	Hs
		587691 CCL19_HUMAN (17-101): 1.59e-22: 87.1: 27.91		NFKB1_HUMAN (271-787): 3.02e-91: 321: 14.56
+	Hs
		528261 CCL5_HUMAN (1-93): 2.44e-26: 96.7: 31.18		REL_HUMAN (273-829): 3.19e-89: 305: 16.16
+	Mm
		486360 CCL2_MOUSE (1-127): 1.23e-46: 149: 100.00		TF65_MOUSE (267-788): 1.37e-71: 252: 17.22
+	Hs
		943970 X3CL1_HUMAN (8-137): 1.41e-34: 125: 23.40		TF65_HUMAN (267-788): 2.88e-74: 260: 17.59
+	Hs
		526567 CCL4_HUMAN (1-93): 1.31e-36: 122: 39.79		TF65_HUMAN (267-788): 2.88e-74: 260: 17.59
+	Hs
		978774 CCL14_HUMAN (1-93): 5.56e-34: 115: 30.85		TF65_HUMAN (267-788): 2.88e-74: 260: 17.59
+	Hs
		528216 CCL2_HUMAN (1-98): 2.89e-33: 114: 52.04		TF65_HUMAN (267-788): 2.88e-74: 260: 17.59
+	Hs
		961427 CCL19_HUMAN (17-101): 1.59e-22: 87.1: 27.91		NFKB2_HUMAN (272-984): 2.65e-77: 278: 16.35
+	Mm
		677067 CCL5_MOUSE (1-93): 9.06e-32: 110: 35.48		TF65_MOUSE (267-788): 1.37e-71: 252: 17.22
+	Hs
		528260 CCL5_HUMAN (1-93): 2.44e-26: 96.7: 31.18		TF65_HUMAN (267-788): 2.88e-74: 260: 17.59
+	Mm
		292678 CCL20_MOUSE (10-97): 1.11e-25: 95.2: 25.56		TF65_MOUSE (267-788): 1.37e-71: 252: 17.22
+	Mm
		953192 CC21B_MOUSE (24-100): 2.91e-23: 90.2: 26.25		RELB_MOUSE (274-719): 5.33e-67: 239: 15.24
+	Hs
		964508 CCL17_HUMAN (4-91): 5.35e-27: 98.3: 29.55		RELB_HUMAN (269-719): 3.66e-63: 228: 15.69
+	Hs
		528259 CCL5_HUMAN (1-93): 2.44e-26: 96.7: 31.18		RELB_HUMAN (269-719): 3.66e-63: 228: 15.69