Protein: SMC2
Structural maintenance of chromosomes protein 2 (DA-box protein SMC2)

Gene: SMC2
Organism: Saccharomyces cerevisiae S288C
Interactions: 57
UniProt ID: P38989

Gene Ontology (top 5):
GO:0000070 - mitotic sister chromatid segregation
GO:0000217 - DNA secondary structure binding
GO:0000785 - chromatin
GO:0000793 - condensed chromosome
GO:0000796 - condensin complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

758766

SMC4
Structural maintenance of chromosomes protein 4

6

16

Small-scale

0.950

High

745516

CND2
Condensin complex subunit 2

5

8

Small-scale

0.916

High

758757

CND1
Condensin complex subunit 1

3

19

Small-scale

0.848

High

758746

SMC3
Structural maintenance of chromosomes protein 3

2

16

Small-scale

0.775

High

758758

CND3
Condensin complex subunit 3

6

10

Small-scale

0.729

High

758762

SGO1
Shugoshin

3

3

Small-scale

0.664

High

700765

SMC1
Structural maintenance of chromosomes protein 1

1

17

High-throughput

0.656

High

758755

SCC2
Sister chromatid cohesion protein 2

1

7

High-throughput

0.618

High

758764

SCC1
Sister chromatid cohesion protein 1

1

20

High-throughput

0.618

High

758768

SMC6
Structural maintenance of chromosomes protein 6

1

15

High-throughput

0.618

High

758745

NDC80
Kinetochore protein NDC80

1

9

Small-scale

0.573

High

491224

HSP71
Heat shock protein SSA1

1

9

High-throughput

0.536

High

511315

SSB1
Ribosome-associated molecular chaperone SSB1

1

11

High-throughput

0.536

High

758753

NU100
Nucleoporin NUP100/NSP100

2

2

Small-scale

0.533

High

758749

PAP2
Poly(A) RNA polymerase protein 2

1

1

Small-scale

0.515

High

758756

KAR5
Nuclear fusion protein KAR5

1

1

High-throughput

0.508

High

758759

BRE1
E3 ubiquitin-protein ligase BRE1

1

12

High-throughput

0.508

High

758763

SLK19
Kinetochore protein SLK19

1

9

High-throughput

0.508

High

454324

TBA1
Tubulin alpha-1 chain

1

9

Small-scale

0.501

High

556048

VATB
V-type proton ATPase subunit B

1

1

High-throughput

0.500

High

705940

SPC29
Spindle pole component 29

1

0

High-throughput

0.486

High

381459

GAL1
Galactokinase

1

0

High-throughput

0.479

High

758761

THI20
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20

1

0

High-throughput

0.479

High

431419

MOD5
tRNA dimethylallyltransferase

1

1

Small-scale

0.479

High

650296

SPT5
Transcription elongation factor SPT5

1

4

High-throughput

0.479

High

662223

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.479

High

663865

TF3B
Transcription factor IIIB 70 kDa subunit

1

4

Small-scale

0.479

High

688244

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

Small-scale

0.479

High

698805

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

3

High-throughput

0.479

High

716237

SPT10
Protein SPT10

1

2

High-throughput

0.479

High

758747

BIR1
Protein BIR1

1

1

Small-scale

0.479

High

758748

VID30
Vacuolar import and degradation protein 30

1

5

High-throughput

0.479

High

758750

APJ1
J domain-containing protein APJ1

1

6

High-throughput

0.479

High

758751

H3
Histone H3

1

9

High-throughput

0.479

High

758754

RUVB1
RuvB-like protein 1

1

2

High-throughput

0.479

High

758765

RIO1
Serine/threonine-protein kinase RIO1

1

5

High-throughput

0.479

High

549733

STI1
Heat shock protein STI1

1

4

High-throughput

0.470

High

523384

SRS2
ATP-dependent DNA helicase SRS2

1

0

Small-scale

0.460

High

360877

TBB
Tubulin beta chain

1

5

Small-scale

0.457

High

758752

UBC7
Ubiquitin-conjugating enzyme E2 7

1

5

High-throughput

0.457

High

355483

H2B1
Histone H2B.1

1

15

High-throughput

0.445

High

366288

HSP82
ATP-dependent molecular chaperone HSP82

1

8

High-throughput

0.445

High

493970

HSP72
Heat shock protein SSA2

1

9

High-throughput

0.445

High

554644

HSP26
Heat shock protein 26

1

2

High-throughput

0.445

High

628049

SIS1
Protein SIS1

1

4

High-throughput

0.445

High

633223

MAS5
Mitochondrial protein import protein MAS5

1

6

High-throughput

0.445

High

694702

HSP7F
Heat shock protein homolog SSE1

1

15

High-throughput

0.445

High

695969

HSP79
Heat shock protein homolog SSE2

1

15

High-throughput

0.445

High

758742

CAJ1
Protein CAJ1

1

5

High-throughput

0.445

High

758743

HSP7E
Heat shock protein SSC3, mitochondrial

1

7

High-throughput

0.445

High

758744

SSB2
Ribosome-associated molecular chaperone SSB2

1

11

High-throughput

0.445

High

758760

VAM6
Vacuolar morphogenesis protein 6

1

2

High-throughput

0.437

High

758741

TCPD
T-complex protein 1 subunit delta

1

0

High-throughput

0.426

High

758767

HSP42
Heat shock protein 42

1

2

High-throughput

0.407

High

751502

HIS9
Histidinol-phosphatase

1

0

High-throughput

0.269

Low

747264

GID4
Vacuolar import and degradation protein 24

1

0

High-throughput

0.249

Low

758769

EFG1P
rRNA-processing protein EFG1

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024