HitPredict

Interactor 1: ANDR (P10275)
Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)
Gene: AR

Interactor 2: UBC9 (P63279)
SUMO-conjugating enzyme UBC9 (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (Ubiquitin carrier protein I) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I) (p18)
Gene: UBE2I

Species: Homo sapiens

Source: dip

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.674

Property	Details
Experiments	10383460, 19692572, 22829593
Identification Methods	two hybrid, enzymatic study, affinity chromatography technology, biochemical
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol and 1 others more... GO:0019899 - enzyme binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 920 Hs			1 158
+	Hs
		369363 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00
+	Hs
		377236 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00
+	Hs
		587151 RXRA_HUMAN (392-902): 7.05e-120: 374: 19.84		UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00
+	Rn
		415139 GCR_RAT (444-920): 1.59e-112: 365: 40.04		UBC9_RAT (1-158): 1.43e-70: 211: 100.00
+	Hs
		437633 MCR_HUMAN (401-920): 3.98e-106: 353: 38.18		UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00
+	Hs
		782515 HNF4A_HUMAN (536-906): 1e-104: 335: 22.85		UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00
+	Hs
		930186 NR1H3_HUMAN (492-903): 9.35e-96: 310: 22.27		UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00
+	Dm
		1181411 Q8WS79_DROME (557-788): 7.93e-28: 120: 29.41		Q7KNM2_DROME (1-158): 1.41e-66: 201: 85.44