Protein: CCL2
C-C motif chemokine 2 (HC11) (Monocyte chemoattractant protein 1) (Monocyte chemotactic and activating factor) (MCAF) (Monocyte chemotactic protein 1) (MCP-1) (Monocyte secretory protein JE) (Small-inducible cytokine A2)

Gene: CCL2
Organism: Homo sapiens
Interactions: 46
UniProt ID: P13500

Gene Ontology (top 5):
GO:0001525 - angiogenesis
GO:0002548 - monocyte chemotaxis
GO:0004672 - protein kinase activity
GO:0005102 - signaling receptor binding
GO:0005576 - extracellular region

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

528206

CCR2
C-C chemokine receptor type 2

14

20

Small-scale

0.976

High

528196

CCL2
C-C motif chemokine 2

3

18

Small-scale

0.866

High

528214

CCL8
C-C motif chemokine 8

2

19

Small-scale

0.802

High

528209

CCL11
Eotaxin

2

18

Small-scale

0.789

High

528223

CCL13
C-C motif chemokine 13

2

18

Small-scale

0.768

High

528198

CSPG2
Versican core protein

1

10

Small-scale

0.724

High

528210

CCR3
C-C chemokine receptor type 3

1

20

Small-scale

0.724

High

364074

PLF4
Platelet factor 4

1

20

High-throughput

0.716

High

528197

CCL5
C-C motif chemokine 5

1

18

High-throughput

0.716

High

486173

IL8
Interleukin-8

1

20

High-throughput

0.692

High

528217

CXCL9
C-X-C motif chemokine 9

1

20

High-throughput

0.692

High

528220

CCL15
C-C motif chemokine 15

1

18

High-throughput

0.692

High

528222

CC4L
C-C motif chemokine 4-like

1

18

High-throughput

0.692

High

528227

CCL26
C-C motif chemokine 26

1

18

High-throughput

0.692

High

528201

CCR1
C-C chemokine receptor type 1

1

20

Small-scale

0.665

High

528211

CCR5
C-C chemokine receptor type 5

1

20

Small-scale

0.665

High

528225

ACKR4
Atypical chemokine receptor 4

1

20

Small-scale

0.665

High

217745

CXL13
C-X-C motif chemokine 13

1

1

High-throughput

0.647

High

528226

XCL2
Cytokine SCM-1 beta

1

18

High-throughput

0.647

High

528207

STAT1
Signal transducer and activator of transcription 1-alpha/beta

3

5

Small-scale

0.640

High

134357

ACKR2
Atypical chemokine receptor 2

1

20

Small-scale

0.618

High

528219

ACKR1
Atypical chemokine receptor 1

2

20

Small-scale

0.595

High

528215

TSG6
Tumor necrosis factor-inducible gene 6 protein

1

15

Small-scale

0.536

High

528221

CXL17
C-X-C motif chemokine 17

1

10

High-throughput

0.536

High

528216

TF65
Transcription factor p65

1

20

Small-scale

0.515

High

528204

COIA1
Collagen alpha-1(XVIII) chain [Cleaved into: Endostatin; Non-collagenous domain 1

1

4

Small-scale

0.501

High

528205

MMP12
Macrophage metalloelastase

1

5

Small-scale

0.501

High

528199

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

20

Small-scale

0.479

High

528212

STAT2
Signal transducer and activator of transcription 2

1

5

Small-scale

0.479

High

441416

MET
Hepatocyte growth factor receptor

1

3

Small-scale

0.445

High

522737

SRC
Proto-oncogene tyrosine-protein kinase Src

1

2

Small-scale

0.445

High

173263

S22A2
Solute carrier family 22 member 2

1

1

Small-scale

0.439

High

173337

S22A1
Solute carrier family 22 member 1

1

1

Small-scale

0.439

High

204535

PROM1
Prominin-1

1

0

Small-scale

0.438

High

217770

ORC4
Origin recognition complex subunit 4

1

1

Small-scale

0.437

High

528200

MCM3
DNA replication licensing factor MCM3

1

2

Small-scale

0.437

High

528202

MCM7
DNA replication licensing factor MCM7

1

1

Small-scale

0.437

High

528208

MCM2
DNA replication licensing factor MCM2

1

2

Small-scale

0.437

High

528224

CDC6
Cell division control protein 6 homolog

1

1

Small-scale

0.437

High

528213

RNF4
E3 ubiquitin-protein ligase RNF4

2

0

High-throughput

0.316

High

528228

TMX2
Thioredoxin-related transmembrane protein 2

2

0

High-throughput

0.316

High

528203

MOT8
Monocarboxylate transporter 8

1

0

High-throughput

0.251

Low

264167

CDC45
Cell division control protein 45 homolog

1

0

Small-scale

0.249

Low

517028

PCNA
Proliferating cell nuclear antigen

1

0

Small-scale

0.249

Low

528218

ORC2
Origin recognition complex subunit 2

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024