Interactor 1: ESYT2 (A0FGR8)
Extended synaptotagmin-2 (E-Syt2) (Chr2Syt)
Gene: ESYT2
Interactor 2: ESYT1 (Q9BSJ8)
Extended synaptotagmin-1 (E-Syt1) (Membrane-bound C2 domain-containing protein)
Gene: ESYT1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.93 | 1.00 | 0.966 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 37931956, 37071682, 39358380, 22119785, 35271311, 40437099, 27065097, 23791178 |
| Identification Methods | proximity labelling technology, cross-linking study, affinity chromatography technology, anti tag coimmunoprecipitation, pull down |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | C2~C2, C2~SMP_LBD, SMP_LBD~SMP_LBD |
| Common GO terms | GO:0005509 - calcium ion binding GO:0005544 - calcium-dependent phospholipid binding GO:0005789 - endoplasmic reticulum membrane GO:0005886 - plasma membrane GO:0008429 - phosphatidylethanolamine binding and 4 others more... |
| Homologous interactions | 18 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
