HitPredict

Interactor 1: ANDR (P10275)
Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)
Gene: AR

Interactor 2: MEP50 (Q9BQA1)
Methylosome protein WDR77 (Androgen receptor cofactor p44) (Methylosome protein 50) (MEP-50) (WD repeat-containing protein 77) (p44/Mep50)
Gene: WDR77

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	12972618, 23734213
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0008284 - positive regulation of cell population proliferation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 920 Hs			1 342
+	Hs
		487745 ANDR_HUMAN (1-920): 0: 966: 100.00		WDR33_HUMAN (58-331): 3.52e-67: 230: 17.86
+	Hs
		245554 ANDR_HUMAN (1-920): 0: 966: 100.00		TBL1X_HUMAN (162-342): 3.97e-28: 116: 15.46
+	Hs
		487742 ANDR_HUMAN (1-920): 0: 966: 100.00		TBL1R_HUMAN (206-337): 3.38e-19: 90.1: 13.01
+	Hs
		487288 ANDR_HUMAN (1-920): 0: 966: 100.00		WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79
+	Hs
		370311 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		MEP50_HUMAN (1-342): 6.74e-81: 251: 100.00
+	Hs
		1269468 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		MEP50_HUMAN (1-342): 6.74e-81: 251: 100.00
+	Hs
		1269553 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		WDR33_HUMAN (58-331): 3.52e-67: 230: 17.86
+	Hs
		725512 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		COPB2_HUMAN (54-331): 3.17e-47: 172: 18.38
+	Hs
		377562 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		FBXW7_HUMAN (3-236): 5.23e-43: 159: 14.29
+	Hs
		369669 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		TAF5_HUMAN (178-328): 1.2e-21: 98: 18.42
+	Hs
		370377 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		TBL1R_HUMAN (206-337): 3.38e-19: 90.1: 13.01
+	Hs
		370309 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		TBL1Y_HUMAN (207-337): 6.68e-19: 89.3: 14.38
+	Hs
		369305 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79
+	Hs
		196938 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		PRP4_HUMAN (253-341): 3.86e-10: 62.8: 13.40
+	Hs
		369932 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		WDR5B_HUMAN (3-106): 2.76e-09: 59.7: 7.90
+	Hs
		1074801 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		TAF5_HUMAN (178-328): 1.2e-21: 98: 18.42
+	Hs
		1269548 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		TBL1R_HUMAN (206-337): 3.38e-19: 90.1: 13.01
+	Hs
		1269467 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		TBL1Y_HUMAN (207-337): 6.68e-19: 89.3: 14.38
+	Hs
		903403 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79
+	Hs
		197064 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		PRP4_HUMAN (253-341): 3.86e-10: 62.8: 13.40