HitPredict

Interactor 1: DNAK (P0A6Y8)
Chaperone protein DnaK (HSP70) (Heat shock 70 kDa protein) (Heat shock protein 70)
Gene: DNAK

Interactor 2: THIO2 (P0AGG4)
Thioredoxin 2 (Trx-2) (EC 1.8.1.8) (Protein-disulfide reductase)
Gene: trxC

Species: Escherichia coli K-12

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.39	0.60	0.484

Property	Details
Experiments	15690043
Identification Methods	tandem affinity purification, pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0008270 - zinc ion binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 638 Ec			1 139
+	Hs
		537530 HSP7C_HUMAN (2-605): 0: 846: 47.82		TXND5_HUMAN (41-139): 8.4e-30: 113: 26.21
+	At
		653925 HS701_ARATH (2-635): 0: 845: 47.25		TRXH1_ARATH (38-139): 4.47e-32: 111: 36.28
+	Hs
		536575 HSP7C_HUMAN (2-605): 0: 846: 47.82		PDIA3_HUMAN (30-137): 2.69e-27: 106: 24.78
+	Hs
		452139 HSP7C_HUMAN (2-605): 0: 846: 47.82		PDIA1_HUMAN (34-137): 6.95e-26: 103: 22.02
+	Hs
		536405 HSP7C_HUMAN (2-605): 0: 846: 47.82		PDIA4_HUMAN (45-120): 6.21e-13: 66.2: 36.71
+	Mm
		801615 HSPA9_MOUSE (2-624): 0: 697: 60.54		THIOM_MOUSE (3-139): 3.15e-38: 128: 23.74
+	So
		236198 O50047_SPIOL (4-635): 0: 681: 59.18		TRXM_SPIOL (19-139): 8.36e-40: 133: 34.43
+	Ss
		910411 DNAK1_SYNY3 (1-619): 0: 577: 51.13		THIO_SYNY3 (35-139): 1.1e-37: 125: 47.17
+	Hs
		535083 BIP_HUMAN (1-599): 0: 530: 50.65		PDIA6_HUMAN (11-139): 8.47e-34: 123: 19.85
+	Hs
		535301 BIP_HUMAN (1-599): 0: 530: 50.65		TXND5_HUMAN (41-139): 8.4e-30: 113: 26.21
+	Hs
		534689 BIP_HUMAN (1-599): 0: 530: 50.65		PDIA3_HUMAN (30-137): 2.69e-27: 106: 24.78
+	Hs
		452138 BIP_HUMAN (1-599): 0: 530: 50.65		PDIA1_HUMAN (34-137): 6.95e-26: 103: 22.02
+	At
		1424594 BIP1_ARATH (1-605): 0: 530: 49.84		PDI14_ARATH (31-138): 1.16e-18: 82.6: 20.18
+	Rn
		448096 BIP_RAT (1-599): 0: 531: 50.65		DJC10_RAT (38-113): 2.94e-14: 70.1: 42.86
+	Mm
		627493 BIP_MOUSE (1-599): 0: 531: 50.65		DJC10_MOUSE (38-114): 2.92e-14: 70.1: 41.03
+	Hs
		535274 BIP_HUMAN (1-599): 0: 530: 50.65		DJC10_HUMAN (46-113): 5.79e-14: 69.3: 45.59
+	Hs
		534571 BIP_HUMAN (1-599): 0: 530: 50.65		PDIA4_HUMAN (45-120): 6.21e-13: 66.2: 36.71