Interactor 1: PUR7 (P0A7D7)
Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6) (SAICAR synthetase)
Gene: purC

Interactor 2: PUR7 (P0A7D7)
Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6) (SAICAR synthetase)
Gene: purC

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.57 1.00 0.757

The method score is based on:

Property Details
Experiments 36748301, 16858726
Identification Methods two hybrid, blue native page
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains SAICAR_synt~SAICAR_synt
Common GO terms GO:0004639 - phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0006189 - 'de novo' IMP biosynthetic process
GO:0009236 - cobalamin biosynthetic process
and 2 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 237
Ec

1 237
+ Hs
+ Dm
+ Ce
+ Cj

Service provided by Combinatics, Japan

Last updated: 11Aug2025