Interactor 1: PUR6 (Q9I7S8)
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS) (Protein adenosine-5) [Includes: Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6) (SAICAR synthetase); Phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) (AIR carboxylase) (AIRC)]
Gene: Paics
Interactor 2: PUR6 (Q9I7S8)
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS) (Protein adenosine-5) [Includes: Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6) (SAICAR synthetase); Phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) (AIR carboxylase) (AIRC)]
Gene: Paics
Species: Drosophila melanogaster
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.43 | 1.00 | 0.656 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 14605208 |
| Identification Methods | two hybrid |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | AIRC~AIRC, AIRC~SAICAR_synt, SAICAR_synt~SAICAR_synt |
| Common GO terms | GO:0004638 - phosphoribosylaminoimidazole carboxylase activity GO:0004639 - phosphoribosylaminoimidazolesuccinocarboxamide synthase activity GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005829 - cytosol and 1 others more... |
| Homologous interactions | 6 |
Homologous interactions
Color coding for hit scores 
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| + | Ec |  |
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
