HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: KAPCA (P17612)
cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)
Gene: PRKACA

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.60 0.753

The method score is based on:

Property Details
Experiments 19014373, 17045592, 23962722, 10840038, 9771888, 10090741, 9546672, 21127069, 12435421, 35063084
Identification Methods enzymatic study, anti tag coimmunoprecipitation
Interaction Type direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0016607 - nuclear speck
and 3 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 758
Hs

1 351
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+ Rn
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+ Bt

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024