HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: RBP56 (Q92804)
TATA-binding protein-associated factor 2N (68 kDa TATA-binding protein-associated factor) (TAF(II)68) (TAFII68) (RNA-binding protein 56)
Gene: TAF15

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	26269332, 35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 592
+	Hs
		496876 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		EWS_HUMAN (4-383): 3.73e-35: 142: 32.96
+	Hs
		496444 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		FUS_HUMAN (8-381): 2.72e-32: 132: 39.28
+	Hs
		212098 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		HTSF1_HUMAN (113-325): 5.58e-31: 130: 18.06
+	Hs
		496999 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		EIF3A_HUMAN (314-591): 5.41e-22: 103: 18.21
+	Mm
		498083 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		Q8BQ46_MOUSE (1-394): 3.73e-35: 141: 94.16
+	Mm
		498044 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		EWS_MOUSE (4-383): 9.82e-32: 132: 33.26
+	Hs
		967173 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		EWS_HUMAN (4-383): 3.73e-35: 142: 32.96
+	Hs
		726817 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		FUS_HUMAN (8-381): 2.72e-32: 132: 39.28
+	Hs
		967541 PCLO_HUMAN (46-758): 3.43e-16: 85.9: 9.19		EWS_HUMAN (4-383): 3.73e-35: 142: 32.96
+	Hs
		517999 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		CO6A2_HUMAN (69-393): 1.2e-20: 98.8: 11.04
+	Dm
		435986 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		CO4A1_DROME (430-592): 7.34e-15: 80.3: 20.86
+	Dm
		1370237 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		Q9VMV5_DROME (3-326): 3.91e-13: 74.9: 8.72