HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: NDKB (P22392)
Nucleoside diphosphate kinase B (NDK B) (NDP kinase B) (EC 2.7.4.6) (C-myc purine-binding transcription factor PUF) (Histidine protein kinase NDKB) (EC 2.7.13.3) (nm23-H2)
Gene: NME2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.650

Property	Details
Experiments	28514442, 33961781, 35063084
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005576 - extracellular region GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 152
+	Hs
		496225 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		NDKA_HUMAN (1-152): 1.83e-90: 261: 88.16
+	Hs
		100166 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		F6XY72_HUMAN (1-77): 3.09e-41: 134: 98.70
+	Dm
		445676 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		NDKA_DROME (2-152): 2.24e-86: 250: 77.48